Alex Kessler

If you had ever wondered who laid the blueprint for Lily-Rose Depp’s style, I’d suggest scrolling through the shop girls on this vintage store’s Instagram grid.

Right now, few musicians are as in-demand, as impactful, as soulful, as one fashion-adored, trend-forging rapper from west London. Deep within the confines of his inner circle, novelist Caleb Azumah Nelson meets the most mercurial – and mysterious – man in British music.

Schiaparelli's lobster (1937) Rome-born designer Elsa Schiaparelli's haute couture salons during the '30s may look like a sedate affair

Background Idiopathic intracranial hypertension (IIH) is a complex neurological condition characterized by symptoms of increased intracranial pressure of unclear etiology. While transverse sinus stenosis (TSS) is often present in patients with IIH, how and why it occurs remains unclear.Methods IIH patients and a set of age-matched normal controls were identified from our single-center tertiary care institution from 2016 to 2024. Brain MRIs before treatment were computationally segmented and parcellated using FreeSurfer software. Extent of TSS on MR venograms was graded using the Farb scoring system. Relationship between normalized brain volume, normalized brain-to-CSF volume, and TSS was investigated. Multiple linear regression was conducted to investigate the association between continuous variables, accounting for the covariates body mass index, sex, and age.Results In total, 84 IIH patients (mean age, 29.8 years; 87% female) and 15 normal controls (mean age, 28.1 years) were included. Overall, increasing/worsening TSS was found to be significantly associated with normalized total brain volume (p=0.018, R=0.179) and brain-to-CSF ratio volume (p=0.026, R=0.184). Additionally, there was a significant difference between controls and IIH patients with mild and severe stenosis regarding normalized total brain volume (ANCOVA, p=0.023) and brain-to-CSF ratio volume (ANCOVA, p=0.034). Likewise, IIH patients with severe TSS had a significantly higher brain-to-CSF volume compared with controls (p=0.038) and compared with IIH patients with mild TSS (p=0.038).Conclusions These findings suggest that total brain volume is associated with extent of TSS, which may reflect extramural venous compression due to enlarged brain and/or venous hypertension with associated cerebral congestion/swelling.Data are available upon reasonable request.

An overview of 70s fashion trends.

What’s appropriate for a cocktail dress code can vary depending on the occasion, the time of year, and even the hosts.

Actor, producer, It Girl, and Miu Miu ambassador Sydney Sweeney self-directed her latest photo shoot in the simplest way possible: mirror selfies.

Here’s everything we know so far about the hotly anticipated adaptation of the Grammy winner’s bestselling memoir ‘The Woman in Me’.

The budding pop star, certified scream queen and proto-TikToker talks her new single, over-the-top fashion and the “chill-girl energy” that defines her.

“I don’t want to become a narcissist,” the nascent national treasure tells Raven Smith in the October 2024 issue, gravel laugh rattling. “I don’t want to become a twat.”