Andrew Forbes

It was one of the quickest, yet more successful individual NHL careers, that included a strong rookie season from a former Toronto Maple Leafs’ goaltender.

Fifteen years cooking facing the sea, this is Chef José Carlos García's farewell to his striking Muelle Uno José Carlos García restaurant on Málaga's contemporary marina quayside, where he and his team have cooked since 2011. The special, limited edition menu '15 años cocinando frente al mar' is available until the end of August 2026, before he moves home to Café de París, the family restaurant in La Malagueta where his award-winning culinary career began.

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Objective To evaluate the effects of intravenous iron on red cell transfusion and recovery after cardiac surgery.Design International, multicentre, double blind, placebo controlled randomised trial (ITACS).Setting 33 hospitals across 10 countries. Participants were enrolled between July 2016 and December 2023.Participants 955 adults with anaemia undergoing elective cardiac surgery. Exclusion criteria included haemoglobinopathy or iron storage disorder, renal dialysis, and erythropoietin or intravenous iron given in the previous four weeks.Intervention A computer generated program randomised participants to intravenous iron 1000 mg or placebo 1-26 weeks before surgery. Participants, clinicians, and data collectors were masked to the intervention.Main outcome measures The number of days alive and at home up to 90 days after surgery (primary outcome), red cell transfusion requirements and complications (secondary outcomes).Results Of 2993 screened participants, 955 were enrolled and 921 of the eligible 939 modified intention-to-treat participants were assessed for the primary outcome. The median number of days alive and at home up to 90 days after surgery was 81.1 (interquartile range 74.8-83.7) in patients assigned to intravenous iron and 80.0 (69.5-83.6) in those receiving placebo (adjusted median difference 1.0 day, 95.4% confidence interval 0.0 to 2.1 days, P=0.041). Red cell transfusions were given to 262 patients (61.1%) in the iron group and 302 (68.2%) in the placebo group during their hospital stay (relative risk 0.90, 95% confidence interval 0.82 to 0.99, P=0.027). No differences were observed for major complications or length of hospital stay.Conclusion Among patients with anaemia undergoing elective cardiac surgery, preoperative intravenous iron was associated with a reduction in red cell transfusion and a small improvement in the number of days alive and at home in the first 90 days after surgery. Intravenous iron is an effective component of patient blood management in this setting.Trial registration ClinicalTrials.gov [NCT02632760][1].Data sharing: Study data are available at: . Full analysis code can be viewed at: .[1]: /lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT02632760&atom=%2Fbmj%2F394%2Fbmj-2026-100407.atom

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