Crystal Phend

Key Takeaways Novel in vivo CRISPR-based therapy lonvoguran ziclumeran (lonvo-z) dramatically lowered hereditary angioedema (HAE) attack frequency in the HAELO randomized trial.

A patch-testing study highlights the compounds that account for most of the contact dermatitis from insulin infusion and glucose monitoring devices.

Remibrutinib achieves complete response for the three most common subtypes of chronic inducible urticaria in a phase 3 clinical trial.

Remibrutinib met its primary endpoints in achieving complete response criteria across the three most common subtypes of chronic inducible urticaria in the phase 3 RemIND trial.

— Randomized trial shows no definitive benefit for escalation to higher levels of ventilation

Small randomized trial supports stronger position in guidelines that favor conservative approach

Key Takeaways In observational cohorts, higher vitamin A levels were linked to better lung function in adults and children, with benefit seen with vitamin D among adults as well.

The scientific statement brings together the latest evidence to inform antiplatelet treatment decisions across the continuum of atherosclerotic cardiovascular disease care.

Crystal Phend J Am Coll Cardiol. 2026; doi:10.1016/j.jacc.2026.05.037

Key Takeaways For adults with elevated cardiometabolic risk who usually slept for at least 7 hours per night, body weight increased by 1 lb