By: Daniel Strauss, Julie Kozaili, Ioana Pintescu, Asahi Kasei Bioprocess
This study focused on creating and optimizing a small-scale model of a continuous chromatography-to-virus filtration setup. This model incorporated inline spiking and mixing as the method for testing virus spiking and viral clearance validation. Flow for the filtrations were controlled by the AKTA pump and ran for 72 h.











