Kumar Kunal

The weather department’s nowcast has placed Gautam Buddha Nagar and Ghaziabad in Uttar Pradesh under red alert, while several parts of national capital is under yellow alert.

The active western disturbance is driving widespread thunderstorms, gusty winds (40-80 kmph), isolated hailstorms, and light-to-moderate rainfall or snowfall across northwest India.

Delhi witnessed a hazy morning on Saturday, a day after the national capital recorded its coldest March day in six years. New Delhi:

Extracorporeal carbon dioxide removal (ECCO₂R) has emerged as a supportive therapy for patients with acute respiratory failure, particularly when refractory hypercapnia and respiratory acidosis persist despite standard management. This narrative review summarizes the physiological rationale, current evidence, and clinical applications of ECCO₂R in modern critical care practice. ECCO₂R removes carbon dioxide directly from the bloodstream, thereby facilitating lung-protective ventilation strategies and potentially reducing ventilator-induced lung injury. The technique has been primarily evaluated in patients with acute respiratory distress syndrome (ARDS) and acute exacerbations of chronic obstructive pulmonary disease (AECOPD). In these settings, ECCO₂R may enable the use of lower tidal volumes and reduced airway pressures, and in selected patients, it may decrease the need for invasive mechanical ventilation. Although ECCO₂R has been shown to improve carbon dioxide clearance, correct respiratory acidosis, and optimize ventilatory parameters, randomized trials have not demonstrated a definitive mortality benefit. Its clinical application is also limited by device-related complications, including bleeding, thrombosis, and hemolysis. Furthermore, outcomes are influenced by technical factors such as cannula configuration, blood flow rate, membrane efficiency, and anticoagulation strategy. Ongoing technological advancements and well-designed clinical trials are needed to better define the role of ECCO₂R in contemporary critical care practice.

The weather system is so large that some areas could see between 100 mm and 500 mm of precipitation in the next three days, raising serious concerns about catastrophic flash flooding.

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