Lauren Crawford

Sometimes you gotta do things yourself. When three Game of Thrones stars weren't nominated for Emmys by HBO, they took matters into their

The Golden Globe nominations are here! On Monday (December 9), Marlon Wayans and Skye P. Marshall revealed this year's nominees.

The Opening Ceremony for this year's Summer Games commenced on Friday (July 23) in Tokyo's Olympic Stadium.

Chronological age is a well-established risk factor for Hypertension (HTN), yet while biological ageing markers such as epigenetic age acceleration (EAA), have been associated with HTN, findings are inconsistent. This study aimed to conduct a systematic review and meta-analysis to evaluate the association between EAA, HTN and blood pressure (BP) to provide an understanding of the role of EAA in HTN development and progression. Six databases were searched, and studies which reported associations between DNA and HTN, and/or BP were included. Functional enrichment analysis was conducted using DAVID and STRING to elucidate underlying molecular pathways. From 4334 studies, 165 met the inclusion criteria. Qualitative analysis indicated that 17.0% of studies reporting global methylation and 49.1% of studies reporting gene-specific methylation demonstrated significant associations with HTN and/or BP. A random effects meta-analysis of 16,136 participants from 8 studies using three epigenetic clock algorithms demonstrated that HTN was associated with increased EAA (β: 0.29, 95%Cl: 0.15–0.43; P < 0.0001). All three individual epigenetic clocks demonstrated a positive association between clinically measured HTN and EAA (Horvath β: 0.33, 95%Cl: 0.08–0.58, P = 0.010; Hannum β: 0.64, 95%Cl: 0.09–1.20; PhenoAge β: 1.21, 95%Cl: 0.56–1.86), whereas this relationship was not clear when using self-reported HTN. This study is the first to systematically demonstrate that HTN is associated with EAA. We recommend the use of clinically measured over self-reported HTN in appropriately powered studies of epigenetic age to obtain an accurate understanding of BP regulation/HTN on the epigenome, supporting pathways to translation and development of novel therapeutic targets for HTN.

I don’t know if you’ve ever imagined what the most decorated American athlete of the 2026 Winter Olympics is like, but if you’re like me, it’s hard to picture the level of focus Jordan Stolz operates with.

Because fresh off her latest Olympic victory, Hilary hasn't exactly slowed down. If anything, she's accelerated — turning a post-Olympics run into a full-blown, box office–level press run.

DaBaby 's sophomore album is here! The Charlotte rapper released KIRK at midnight on Friday (September 27); his second project of 2019.

There's something to be said about people who still find a way to encourage others even when they're going through their own struggles.

If Mary Beth Barone has no fans, I'm dead. I was first introduced to the stand-up comedian while scrolling my timeline when I came across

Restoring a Cathedral: The Work and Craftsmanship Behind the Transformation In July, Salford Cathedral will reopen its doors following a three-year programme of restoration, renewal and refurbishment that has transformed the cathedral. The Work Undertaken This project combined large-scale structural repairs with careful heritage conservation and sensitive liturgical renewal. Major Structural Repairs Extensive work was […]