Monika Singh

Abstract: We characterize the modular and norm inequalities for the Dunkl-Hausdorff operator defined on non-negative non-increasing functions in the framework of the weighted Orlicz spaces.

EIGHTH EDITION OF THE PRESTIGIOUS AWARDS RECOGNISES PROJECTS WITH DOMESTIC AND CROSS-BORDER ASIAN APPEAL

IntroductionChildhood blindness is largely attributable to preventable causes. In children with developmental delay, identifying ocular morbidity is particularly challenging due to limited cooperation and associated comorbidities. This study aimed to determine the prevalence and spectrum of refractive errors, strabismus, and other ocular findings among children with developmental delay attending a tertiary care center in South India, and to highlight the importance of early ophthalmic screening in this population.MethodsThis retrospective review included 100 preschool children with developmental delay (aged four months to five years) presenting to the ophthalmology outpatient department of a tertiary care center in South India over a period of two years. Visual impairment was defined as visual acuity below the age-appropriate expected level despite best correction, or, in uncooperative children, based on abnormal fixation behavior and inability to maintain central, steady fixation. Evaluation included visual acuity testing, refraction, ocular alignment assessment, and comprehensive ophthalmic examination.ResultsVisual impairment was observed in 66 (66%) children (95% CI: 56-75). Refractive errors were identified in 84% (95% CI: 75-90) of the cohort, with hypermetropia being the most frequent subtype (65, 78%), followed by myopia (15, 18%) and astigmatism (38, 45%). Strabismus was detected in 12% of children, most frequently exotropia. Causes of developmental delay included prematurity (69%), syndromic associations such as Down syndrome (10%), and miscellaneous factors (21%).ConclusionNearly two-thirds of children with developmental delay had visual impairment, predominantly due to refractive errors and strabismus. Early ophthalmic screening and timely management are essential to reduce preventable visual disability and improve neurodevelopmental outcomes in this vulnerable group.

A 36-year-old female presented with rapidly ascending, flaccid quadriparesis, bulbar, and respiratory failure requiring four days of mechanical ventilation. This presentation was highly atypical, as the neurological symptoms commenced virtually concurrently with an active community-acquired pneumonia (CAP), noted on the fourth day of her febrile prodrome, departing from the classic post-infectious timeline of Guillain-Barré syndrome (GBS). Initial investigations ruled out myopathy (normal creatine phosphokinase (CPK)/creatine kinase-MB (CK-MB)), while subsequent studies established the diagnosis. Nerve conduction velocity (NCV) confirmed non-length-dependent axonal motor polyneuropathy, and cerebrospinal fluid analysis showed albuminocytologic dissociation. The prompt suspicion and diagnosis of acute motor axonal neuropathy (AMAN) allowed for initiation of intravenous immunoglobulin (IVIG) and broad-spectrum antibiotics for the CAP, which resulted in a successful clinical course, including successful extubation, and impressive motor recovery upon discharge. This case report highlights the critical importance of recognizing parainfectious AMAN presentations to ensure timely immunomodulatory therapy in the setting of severe concurrent systemic illness.

By Monika Singh of Wansolwara News Pacific media are facing one of their most challenging reporting environments in their history, marked by

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In situ surface reconstruction of Co-polyoxometalates (Co-POMs) has a significant influence on its electronic and structural properties during oxygen evolution reaction (OER). In this concern, a nove...