Noor Fatima

Recent research has uncovered that cells infected with HIV-1 release exosomes carrying a mix of viral and host components such as proteins, nucleic acids, lipids, and other metabolites.

As electricity costs in Pakistan continue to rise and load-shedding remains a major issue, more homeowners and businesses are turning to solar energy for affordable and sustainable power.

Hira Tariq [email protected] ∙ Aamir Alamgir ∙ ∙ Noor Fatima ∙ Anmol Minaz Highlights

Authors Adnan Khan Noor Fatima Mehran Ullah Bani Nosheen Mehsood Iqra Zia Salma Bashir DOI:

Background: Acute pulmonary embolism (PE) is a critical emergency condition that can lead to rapid hemodynamic compromise and death if not treated promptly.Objective: To assess whether initiating anticoagulation within two hours of emergency department (ED) presentation improves in-hospital outcomes in patients with acute pulmonary embolism.Methods: This retrospective cohort study was conducted at Fauji Foundation Hospital, Rawalpindi, from December 2024 to June 2025. A total of 345 adult patients diagnosed with acute PE between January 2020 and December 2024 were included. Patients were divided into two cohorts: early anticoagulation and delayed anticoagulation (initiated after four hours). Clinical data, including demographics, comorbidities, hemodynamic parameters, laboratory findings, imaging results, and treatment outcomes, were analyzed.Results: Out of 345 patients, 192 (55.6%) received early and 153 (44.4%) delayed anticoagulation. The mean age was 54.8 ± 15.2 years, with 215 (62.3%) males. Mortality was significantly lower in the early group, 14 patients (7.3%), compared to 26 patients (17.0%) in the delayed group (p = 0.006). Early anticoagulation also reduced recurrent thromboembolism, occurring in seven patients (3.6%) versus 14 patients (9.2%) in the delayed group (p = 0.03), as well as ICU admissions-47 patients (24.5%) versus 59 patients (38.6%), respectively (p = 0.008). The mean hospital stay was significantly shorter in the early group (5.8 ± 2.9 days) than in the delayed group (8.4 ± 3.6 days, p < 0.001). No significant difference in major bleeding events was observed between groups (p = 0.48).Conclusion: It is concluded that initiating anticoagulation within two hours of presentation significantly improves survival, decreases recurrence, and shortens hospital stay without increasing bleeding risk. Emergency departments should prioritize rapid diagnostic and treatment pathways to enable early anticoagulation, particularly in resource-limited settings.

Mitral stenosis (MS) is still a significant cause of cardiovascular morbidity and mortality in low- and middle-income countries, despite being nearly eradicated in the developed world. Percutaneous b...

There's a moment when you're sitting in front of your screen, staring at a terminal, and something...

For much of the past, wars have been fought to seize territory, oil and strategic influence. Global wars were characterized by large merchant fleets, weapons and naval forces. But for modern day governments, racing to develop powerful technologies, digital eco-systems, and computing infrastructures is the priority to showcase their dominance in the world.

Authors Komal Mumtaz Noor Fatima Asma Sarwar Manahil Asghar Khan Momina Haq Bushra Abbasi DOI:

Ahsan Zil-E-Ali MBBS Send email to [email protected] ∙ ∙ ∙ … ∙ ∙ Ali Hakimi MD ∙ Faisal Aziz MD, MBA, FACS, DFSVS