Ryner Lai

A 20-year-old male patient presented with shortness of breath that worsened upon physical exercise, such as running. Combined with what felt like bone pain, he has been less physically active recently.

The use of ibrutinib in chronic lymphocytic leukemia (CLL ) can result in persistent benefits and a deepening response, but evidence on whether patients with undetectable minimal residual disease (uMRD) can safely discontinue treatment remains unclear. These findings were presented in a study published in Blood.

Bowen SG, Abdallah N, Pritchett JC, et al. Impact of outpatient CAR T-cell therapy administration on healthcare utilization in patients with

The addition of gabapentin to tramadol during concurrent chemoradiation (CCRT) drastically reduced the need for opioid escalation in patients with

Anselamimab therapy is associated with improved all-cause mortality (ACM) and reduced cardiovascular hospitalizations (CVHs) in patients with kappa immunoglobulin light chain (AL) amyloidosis, according to a study published in the Journal of Clinical Oncology.

A 28-year-old male patient was diagnosed with severe hemophilia B (ie, factor IX levels under 1%) shortly after birth. His family history included a maternal uncle who had the disease.

Oral sonrotoclax was associated with rapid and durable responses among patients with relapsed/refractory (R/R) mantle cell lymphoma (MCL) who were heavily pretreated, according to a study published in Hematologic Malignancy.

Yemen now ranks third highest in the world for measles cases, a sign of its collapsing healthcare system.

Two of three approved gene therapies for hemophilia have left the market and a fourth candidate went to a bankruptcy auction recently and found no buyer. The science worked but the business did not. What went wrong? And what does it mean for every gene therapy program that follows?

A diagnosis of HHT was associated with iron deficiency anemia, mucosal and gastrointestinal bleeding, and solid-organ arteriovenous malformations (AVMs), highlighting the need for early diagnosis, preventative care, and the continued development of effective disease-modifying therapies, according to a study published in Blood.