By: Shinde, Rushikesh , Shivakumar N. Nanjappa, Avichal Kumar, Megha Kamath, Raksha Pai, Vanita Somasekhar, Sanjana Prakash
This study aimed to design flash-release dispersible sublingual wafers of Isosorbide dinitrate (ISDN) by lyophilisation (LYO) by applying the principles of Quality by Design (QbD). Sublingual wafers and films were developed by LYO and solvent casting (SC) techniques respectively by 2 3 factorial design using



