Vinay Kumar

Faculty of Agriculture, Food Science and Environmental Management, Institute of Food Science, University of Debrecen, Böszörményi út 138, 4032 Debrecen, Hungary

Gonda (Uttar Pradesh) [India], April 25 (ANI): As speculation over Uttar Pradesh's Kaiserganj seat deepens, sitting MP Brij Bhushan Singh, who was

Kosuke Ishizuka,1 Shun Yamashita,2, 3 Yuichiro Mine,4 Yukichika Yamamoto,5, 6 Hiroki Kojima,7 Hidehiro Someko,8 Taiju Miyagami4

Fang Gao,1, * Xialin Zhang,2, * Xiaolan Wang,2 Junyan Zhang,3 Fang Wang,1 Yan Zhou,4 Jing Wang,1 Xuewen Li,5 Ruijuan Zhang2

New Delhi/Amethi: Finally, the suspense was over about the Congress candidates from the two high-profile Lok Sabha seats in UP — Amethi and Raebareli as the party leadership on Friday announced that Rahul Gandhi will contest from Raebareli and Gandhi family loyalist Kishori Lal Sharma will fight from Amethi.

Kajal Kumari Sushil Nagar Sakshi Goyal Sonu Maan Vinod Kumar Neeraj Kharor

Ming-Ming Ma,1, * Yao-Yao Xu,2, * Li-Hua Sun,1, * Wen-Jie Cui,1 Miao Fan,3 Su Zhang,4 Lei Liu,5 Ling-Zhi Wu,6 Liu-Cheng Li7

Background: Multidrug-resistant tuberculosis (MDR-TB) patients experience disproportionately worse mental health, with implications for adherence, outcomes, and families. Comprehensive assessments of comorbid depression/anxiety and related factors remain limited.Objective: This study aimed to assess the prevalence, predictors, and qualitative experiences of depression and anxiety in MDR-TB patients and household contacts.Methods: A sequential explanatory mixed methods study was conducted in Gujarat, India, with 403 smear-positive MDR-TB patients and 403 contacts. The quantitative phase administered structured questionnaires on sociodemographic factors, clinical history, depression/anxiety symptoms, and psychosocial stressors (like stigma and social support). Logistic regression models were used. The qualitative phase included in-depth interviews with 30 purposively sampled patients for thematic content analysis. Results were integrated to contextualize quantitative findings.Results: High rates of depression (37.5%, n = 151) and anxiety (45.2%, n = 182) were documented among the MDR-TB patients, significantly greater than household contacts (20.1%, n = 81 and 25.1%, n = 101, respectively). For depression, older age (adjusted odds ratio (AOR) 2.03, 95% CI 1.01-4.05), female gender (AOR 2.5, 95% CI 1.1-6.0), divorced/widowed status (AOR 3.8, 95% CI 1.1-8.0), financial constraints, substance abuse (AOR 1.7, 95% CI 1.1-2.7), greater disease severity (AOR 1.8, 95% CI 1.5-2.2), medication side effects (AOR 2.4, 95% CI 1.2-4.6), and perceived stigma (AOR 3.2, 95% CI 1.1-5.3) emerged as significant risk factors. For anxiety, significant predictors were less social support (AOR 0.81, 95% CI 0.71-0.86), higher perceived stigma (AOR 2.2, 95% CI 1.1-6.3), greater disease severity (AOR 2.6, 95% CI 1.3-4.0), and more medication side effects (AOR 3.3, 95% CI 1.1-5.5). Prominent themes included psychological impacts like depression and anxiety, experiences of stigma and caretaking challenges, and recommendations for comprehensive patient support services.Conclusion: MDR-TB patients experience a substantially higher dual disease burden of depression and anxiety, elevating the risk for adverse outcomes and transmission. Improving psychosocial support is vital to patient-centric care pathways for vulnerable groups. Mixed methods provide comprehensive evidence to inform integrated physical and mental health services.

Abstract Endophytes share a complex intimate relationship due to which they are capable of synthesizing metabolites that are either similar or derivative of host bioactive compounds.

PM Modi targeted the Opposition INDIA bloc with “corruption'' claim with Rahul Gandhi hitting back and raising the issue of electoral bonds “scam.''