Medical Xpress

Dozens of research teams around the world are working to halt, treat and even prevent Alzheimer's disease, which silently develops in the brain for more than a decade before symptoms appear. Although recent years have brought important advances, researchers continue to search for therapies that can more effectively alter the course of Alzheimer's and other forms of dementia.

A new drug offers hope for people with hypertrophic cardiomyopathy, the world's most common inherited heart disease. The TEMPEST trial, led by University of Manchester researchers, tested the drug—called trientine—in 154 adults with the condition in a yearlong, placebo-controlled study. The study is published in the European Heart Journal.

The skull heals its cracks, the bruises fade, the swelling subsides and the bleeding stops. From the outside, a traumatic blow to the head, whether from a battlefield blast, car crash or even a tackle gone wrong, may seem like it's healed. But that's only the opening act of traumatic brain injury (TBI).

New research presented at the International Congress on Obesity (ICO2026), hosted by the World Obesity Federation (WOF) in Mexico City, Mexico, (15–17 July) asks what is driving the obesity pandemic.

Parkinson's disease is the second most common neurodegenerative disease worldwide after Alzheimer's disease and, according to the World Health Organization, one of the fastest-growing neurological disorders. Yet genetic research into the disease has so far relied almost exclusively on people of European ancestry. This is a problem because the genetic causes of the disease depend strongly on a person's ancestry.

We may age at different rates, but none of us escapes aging. A study in mice and human cells by Stanford Medicine researchers pins much of the blame on a particular type of immune cell's increasing inability, with advancing age, to gobble up another immune cell type.

From disease surveillance to clinical care, artificial intelligence is transforming health. As AI becomes more deeply embedded in decisions affecting population health, a new editorial argues that realizing AI's full potential requires public health leadership alongside technical innovation.

By analyzing individual cancer cells, researchers from the Université Libre de Bruxelles (ULB) discovered the transcriptional regulators governing epithelial-to-mesenchymal transition (EMT) in tumors and identified key master regulators that control metastasis, revealing potential therapeutic vulnerabilities to block metastatic dissemination.

Being overweight and obesity may contribute to significantly more cancer cases than previously thought. This is the conclusion reached by researchers at the German Cancer Research Center (DKFZ). Their analysis shows that when more accurate measures of body fat and methodological biases are considered, more than 10% of all cancer cases can be attributed to increased body weight—nearly twice as many as previous estimates suggested.

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