Amjad Ali

Abstract In recent years, the analysis of metagenomic data to recover unculturable microbes has revolutionized microbial genomics by rapidly expanding the reference genome catalog.

Open Access Review by Shehwaz Anwar Shehwaz Anwar SciProfiles Scilit Preprints.org Google Scholar

Apigenin is a powerful flavone compound found in numerous fruits and vegetables, and it offers numerous health-promoting benefits. Many studies have evidenced that this compound has a potential role as an anti-inflammatory and antioxidant compound, making it a promising candidate for reducing the risk of pathogenesis. It has also been found to positively affect various systems in the body, such as the respiratory, digestive, immune, and reproductive systems. Apigenin is effective in treating liver, lung, heart, kidney, neurological diseases, diabetes, and maintaining good oral and skin health. Multiple studies have reported that this compound is capable of suppressing various types of cancer through the induction of apoptosis and cell-cycle arrest, suppressing cell migration and invasion, reduction of inflammation, and inhibiting angiogenesis. When used in combination with other drugs, apigenin increases their efficacy, reduces the risk of side effects, and improves the response to chemotherapy. This review broadly analyzes apigenin's potential in disease management by modulating various biological activities. In addition, this review also described apigenin's interaction with other compounds or drugs and the potential role of nanoformulation in different pathogeneses. Further extensive research is needed to explore the mechanism of action, safety, and efficacy of this compound in disease prevention and treatment.

Environmental Science and Pollution Research , Jul 2024 Environmental Science and Pollution Research (2024) 31:46099

In this article, we initially provided the relationship between the RL fractional integral and the Caputo fractional derivative of different orders. Additionally, it is clear from the literature that studies into boundary value problems involving multi-term operators have been conducted recently, and the aforementioned idea is used in the formulation of several novel models. We offer a unique coupled system of fractional delay differential equations with proper respect for the role that multi-term operators play in the research of fractional differential equations, taking into account the newly established solution for fractional integral and derivative. We also made the assumptions that connected integral boundary conditions would be added on top of -fractional differential derivatives. The requirements for the existence and uniqueness of solutions are also developed using fixed-point theorems. While analyzing various sorts of Ulam's stability results, the qualitative elements of the underlying model will also be examined. In the paper's final section, an example is given for purposes of demonstration.

Northwest Institute of Eco-Environment and Resources (NIEER), Chinese Academy of Sciences, Lanzhou 730000, China

Key Laboratory of Ecological Safety and Sustainable Development in Arid Lands, Northwest Institute of Eco-Environment and Resources, Chinese Academy of Sciences, Lanzhou 730000, China

Authors Zahid Ali Amjad Ali Muhammad Tariq Farman Hira Fatima Waseem Tariq Aziz DOI: Keywords:

Authors Noureen Fazal Amjad Ali DOI: Keywords: nursing profession and transgender, Nursing Shortage

Background: Coronary and carotid artery diseases are manifestations of a systemic atherosclerotic process, often coexisting in patients affected by both conditions. This association emphasizes the importance of evaluating both coronary and carotid atherosclerosis in high-risk individuals. Ultrasound 2D shear-wave elastography (2D-SWE) has shown promise as a noninvasive technique for assessing carotid plaque stiffness. This prospective pilot study aimed to assess carotid plaque stiffness in patients undergoing coronary artery bypass grafting (CABG) and those not scheduled for the procedure as a control group. Methods: 32 patients (17 CABG and 15 controls) were recruited, collectively presenting 43 carotid plaques. Bilateral carotid ultrasound was performed using a high-resolution linear transducer. Plaque stiffness was quantified via 2D-SWE, expressed in shear-wave velocity (SWV, m/s) and Young’s modulus (YM, kPa). Plaque characteristics, including GSM, were quantified. Intra-observer reproducibility was evaluated with intraclass correlation coefficients (ICCs) and Bland–Altman plots. Statistical differences and correlations were assessed using Mann–Whitney U and Spearman’s correlation tests. Results: Carotid plaques in the CABG group exhibited significantly lower stiffness compared to controls (median stiffness SWV: 3.64 m/s vs. 4.91 m/s, p < 0.0001; YM: 20.96 kPa vs. 72.54 kPa, p < 0.0001). ICCs demonstrated excellent reproducibility for stiffness measurements (SWV: ICC = 0.992; YM: ICC = 0.992), with minimal bias in measurements. A positive correlation was observed between 2D-SWE and GSM values (SWV: r = 0.343, p = 0.024; YM: r = 0.340, p = 0.026). Conclusions: Ultrasound 2D-SWE has shown promise as a reliable tool for quantifying carotid plaque stiffness, demonstrating high reproducibility and a significant correlation with GSM. The observed reduction in plaque stiffness among CABG patients highlights its potential as a valuable parameter for identifying high-risk plaques and assessing cerebrovascular risk in patients undergoing CABG.