Ashley Killen

Researchers at Cleveland Clinic intend to expand their study of a novel vaccine designed to prevent triple-negative breast cancer.An ongoing phase 1A clinical trial — expected to conclude in the fourth quarter of this year — is investigating the vaccine for patients who completed treatment for early-stage, triple-negative breast cancer within the past 3 years and remain tumor free but

A prospective phase 2 trial that evaluated risk-enabled therapy after neoadjuvant chemotherapy for muscle-invasive bladder cancer failed to meet a prespecified threshold of noninferiority, according to study results.The single-arm RETAIN BLADDER trial included 70 patients (median age, 70 years; range, 47-83; 74% male; 92% white) who completed three cycles of neoadjuvant MVAC chemotherapy.

Haptoglobin gene expression in the blood appeared associated with anthracycline-related cardiomyopathy among childhood cancer survivors, according to study results.The findings provide insights into the role genetic variants associated with haptoglobin RNA levels have in anthracycline-related cardiac dysfunction, as well as a potential mechanistic explanation for the role of oxidative damage

Massage therapy can benefit young patients with cancer or hematologic conditions, according to retrospective study results.Findings showed children, adolescents and young adults who underwent massage therapy sessions reported improvements in stress, pain and anxiety.

Survival for patients with metastatic colorectal cancer has improved steadily since 2012, according to retrospective study results.Researchers attributed this trend to several factors, including use of immunotherapy, surgical resection of liver metastases and use of third-line chemotherapy.

Community oncologists who received peer coaching from cancer genetics experts more frequently ordered genetic testing for their patients, according to study results.Additional support is necessary to ensure genetic testing is offered to all patients who meet criteria, researchers concluded.

The availability of highly effective targeted agents has changed the treatment landscape for chronic lymphocytic leukemia, but key questions about optimal strategies remain, according to a review published in JAMA.“In the past 10 years or so, we have made a lot of progress in terms of finding novel therapeutic agents ... that have replaced chemoimmunotherapy, both in the first-line and

A nurse-created algorithm helped determine which patients with multiple myeloma exhibited the highest risk for pneumonia, according to study results.Cancer or its treatments can lead to low white blood cell counts.

A high percentage of people with cancer exhibit what are known as SPPADE symptoms, according to study results.Investigators interviewed 31,886 people with cancer and assessed them for these symptoms, which include sleep disturbance, pain, physical function impairment, anxiety, depression, and low energy or fatigue.

An oncology financial navigation intervention decreased financial toxicity among patients with blood cancers and their caregivers, according to study results.The intervention — called Coverage and Cost-of-Care Links (CC Links) — also received high ratings for acceptability and appropriateness, findings showed.