Carmen Leitch

Alzheimer's disease is a common disease of aging that doctors have been aware of for decades. But scientists are still learning about the mechanisms that drive it. Alzheimer's is characterized by the buildup of aberrant proteins: amyloid plaques and tau tangles. New research has revealed more about how tau can spread to new parts of the brain, driving the progression of the disease. This work, which used a mouse model to show that a protein known as Arc is crucial to this process, has been

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As we get older, our bodies change in many ways. For example, muscles tend to get weaker as people age. Researchers have now learned more about why that happens, and why exercise is still known to be a reliable way to counteract that process. This work showed that a molecule called DEAF1 that can regulate gene activity appears to trigger overactivity in a pathway known as mTORC1 that maintains muscles.

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Cells transcribe active genes into messenger RNA molecules, using a crucial complex known as RNA polymerase II. These mRNA transcripts are then translated

A Fungus & Bacterium Have a Symbiosis that Changes the Severity of Fungal Disease

The community of microbes in the human gut serves many important roles. New research has shown that certain bacteria in the gut microbiome can help push vitamin A and the signals it activates towards crucial immune cells called T cells. The signals triggered by vitamin A are important to T cell development. T cells are on the front lines of the immune system, and work to destroy pathogens and foreign invaders. This work, which was