Carolina Borges

SOUTHWEST MIAMI-DADE, FLA. (WSVN) - For the first time in its history, Zoo Miami has successfully hatched threatened Texas horned lizards, marking a significant milestoneRead More

HIALEAH, FLA. (WSVN) - A serious crash on the Palmetto Expressway (State Road 826) near 74th Street caused significant traffic disruptions Wednesday morning, with a helicopter airlifting a person involved in the accident.

OPA-LOCKA, FLA. (WSVN) - Authorities are investigating a fatal accident involving a scooter that occurred at the intersection of Northwest 27th Street and Ali Baba Avenue in Opa-locka.

MIAMI (WSVN) - A 38-year-old man has been arrested after being caught on surveillance footage peeking through an apartment window and engaging in lewd behavior in Miami.

CAPE CORAL, Fla. (WSVN) — A 12-year-old girl escaped a house fire on Tuesday morning, saving not only herself but also the family’s four dogsRead More

MIAMI (WSVN) - A 38-year-old man has been arrested after being caught on surveillance footage peeking through an apartment window and engaging in lewd behaviorRead More

MIAMI-DADE COUNTY, Fla. (WSVN) — Just two weeks into the new school year, Miami-Dade Police are raising concerns over a startling rise in school bus violations.

MIRAMAR, FLA. (WSVN) - Tensions are rising between Miramar city officials and Miami-Dade County as plans for a new incinerator near the city border continue to progress.

PINECREST, FLA. (WSVN) - Miami Dolphins quarterback Tua Tagovailoa and his foundation made a good call by donating a brand new flag football field toRead More

Recent advancements have highlighted the potential of cannabis and its phytocannabinoids (pCBs) in skin health applications. These compounds, through their interaction with the endocannabinoid system (ECS), show promise for skin health products. Their ability to regulate inflammation, oxidative stress and cell proliferation makes them useful in addressing skin problems such as inflammation, scarring, healing, acne and aging, positioning them as valuable tools for innovative skincare solutions. In the present work, the cellular and molecular effects of proprietary pCB-based formulations on ECS modulation, inflammation and skin regeneration were investigated. Using human dermal fibroblasts (HDF) and keratinocytes (HaCaT), the effect of formulations in both pre-treatment and treatment scenarios following exposure to stress-inducing agents was assessed. Key molecular markers were analyzed to tackle their efficacy in mitigating inflammation and promoting structural integrity and regeneration. In vitro results showed that these formulations significantly reduced inflammation, promoted skin regeneration and improved structural functions. In vivo studies confirmed that the formulations were well-tolerated and led to noticeable improvements in skin health, including enhanced barrier function. This study demonstrates the safety and efficacy of pCB-based formulations for cosmeceutical applications. By combining molecular analysis with in vivo testing, this research provides new insights into the therapeutic potential of pCBs for managing various skin conditions.