Messenger ribonucleic acid (mRNA)-based therapeutics and the potential of mRNA as a treatment for various conditions has been researched for decades. A key challenge remains finding a delivery system that enables enough of the mRNA to reach target tissues safely without causing adverse effects. Lipid nanoparticles have been studied since the 1960s, but widespread use and optimization of delivery for mRNA therapeutics, including vaccines, really came to the forefront during COVID-19. While these vaccines saved countless lives, current lipid nanoparticle-mRNA delivery systems still face limitations that researchers are working to improve for broader therapeutic use.
Claire Kowalick is the Editor In Chief for Times Record News, focusing on local news in Wichita Falls, Texas. She has a strong background in journalism and has contributed to various publications, including Angelo Homeworx LLC and Yahoo News. Claire's work covers a range of topics, from community events and human interest stories to local politics and social issues.