David Greenfield

Insulin resistance is a risk factor for type 2 diabetes and exercise can improve insulin sensitivity. However, following exercise high circulating fatty acid (FA) levels might counteract this. We hypothesized that such inhibition would be reduced by forcibly increasing carbohydrate oxidation through pharmacological activation of the pyruvate dehydrogenase complex (PDC). Insulin-stimulated glucose uptake was examined with a cross-over design in healthy young men (n = 8) in a previously exercised and a rested leg during a hyperinsulinemiceuglycemic clamp five hours after one-legged exercise with: 1) infusion of saline, 2) infusion of intralipid imitating circulating FA levels during recovery from whole-body exercise, and 3) infusion of intralipid + oral PDC-activator, dichloroacetate (DCA). Intralipid infusion reduced insulin-stimulated glucose uptake by 19% in the previously exercised leg, which was not observed in the contralateral rested leg. Interestingly, this effect of intralipid in the exercised leg was abolished by DCA, which increased muscle PDC activity (130%) and flux (acetylcarnitine 130%) and decreased inhibitory phosphorylation of PDC on Ser

The partnership between Omron and Roeq enables greater focus on intralogistics projects for faster execution.

KUKA's new KMP 1500 omnidirectional autonomous mobile robot is designed to work flexibly in matrix production operations.

Acoustic guitar manufacturer Dowina shows how Vectary's platform can be used for millions of custom configuration possibilities.

Schneider Electric's Heather Cykoski explains what constitutes a smart factory, how the concept is advancing at manufacturing facilities across the globe, its connection to digital transformation initiatives and the biggest challenges manufacturers face when seeking to become a smart factory.

April 25, 2024

NIST offers manufacturers an array of cybersecurity information related to Internet of Things technologies—from device selection and implementation guidance to outlines on what capabilities IoT devices should feature.

Sick USA's Aaron Rothmeyer explains LiDAR sensors, how they differ from other sensors commonly used in the manufacturing industries and how they can be applied in quality control operations.

When I started covering automation and robotics in the early 1990s, I heard from a few experienced editors in the field that, unfortunately, I had missed the heyday of robotics. According to them, industrial robotics peaked in the 1980s, with robotic sales dwindling in the early 1990s as industry—mostly automotive manufacturers—had installed about all the robots they were going to buy. Needless to say, such comments were extremely shortsighted. I would say that, even as advanced as robotic technologies appear today, we're only seeing the beginnings of their potential in industry and elsewhere. The Automate 2024 highlights in this video are testament to the exploding robotics applications and technology advances happening now.

Teradyne Robotics' work with Nvidia is expected to bring about an inflection point in technology that will enable robots to operate more precisely in unstructured and changing environments and scale new robotic applications at companies of all sizes.