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James Cook's coverage indicates a focus on business and industry, particularly in the energy sector including topics such as power plants, gas turbines, fuel cells, and hydrogen. The emphasis on press releases and private sector announcements suggests that he is likely to be interested in news from companies within these industries.
Given the technical nature of the topics covered by James Cook, pitches should offer detailed insights into new technologies or significant developments within the energy sector. Additionally, experts who can provide analysis of trends affecting businesses in this space would likely attract his attention.
It seems that James does not have a specific geographic focus but instead covers international industry news related to energy and technology advancements.
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By: Benjamin J Muller, James Cook, Lin Schwarzkopf, Toamasina Madagascar, Nomenjanahary Faly Randriamanantena, Rodino Fetraharijaona Harison
BACKGROUND Invasive species are a major threat to biodiversity on a global scale.
By: James Cook
Stefano Gianatti of Ansaldo Energia says installing baseload flexible generation is key to supporting European countries struggling with renewable energy intermittency.
By: James Cook
EthosEnergy will conduct routine inspections and preventive maintenance at the 850-MW facility that houses Siemens Energy’s turbines and gensets.
By: James Cook
President Trump and the Prime Minister of Saudi Arabia’s visit prompted the collaboration with GE Vernova to potentially supply advanced heavy-duty gas turbines built in Greenville, SC.
By: James Cook
The marine compressed air system, equipped with Smart Air compressors and air dryers, will allow the VARD 8-02 trawler to operate with improved fuel economy.
By: James Cook
The Town of Rock Hall is excited to share a slate of transformative projects, many recently completed, others actively underway, and several preparing to break ground.
By: James Cook
Nuclitalia will focus on small modular reactors, evaluate sustainable nuclear power designs, establish requirements, and conduct technical-economic analyses.
By: James Cook
The Flame Tracker Increased Low Gain is more sensitive to low-light environments, allowing it to quickly identify flames and trigger shutdown to prevent damage or explosion.
By: James Cook
The floating storage and regasification unit will begin executing LNG regasification services at the LNG terminal in the Port of Pepillo Salcedo in September 2025.
By: Mizanur, Md. Taohid, Md. Abdulla Al
The rise of multidrug-resistant (MDR) microorganisms, particularly Escherichia coli, poses a significant threat to global public health, necessitating the development of alternative treatments. This study investigates the antibacterial properties of methanolic Punica granatum (pomegranate) leaf extract (MPGL) against MDR E. coli and explores its potential as a source of natural inhibitors for the CTX-M-9 beta-lactamase enzyme, a key contributor to antibiotic resistance. The disc diffusion assay revealed that MPGL exhibited significant antibacterial activity, with the highest inhibition zone of 16.67 ± 0.29 mm at 100 µg/disc. Additionally, an in silico approach was employed to identify potential inhibitors from P. granatum phytochemicals. Molecular docking studies demonstrated strong binding affinities of Epicatechin, Kaempferol, and Apigenin to the CTX-M-9 beta-lactamase protein (PDB ID: 1YLY), with binding energies of -6.25, -5.23, and − 5.21 kcal/mol, respectively. These compounds also showed favorable pharmacokinetic and toxicity profiles in ADMET analysis, indicating their potential as safe and effective therapeutic agents. Molecular dynamics simulations further confirmed the stability of these compounds in complex with the target protein over a 100 ns trajectory, with Epicatechin showing the most stable interactions. The study highlights the promising antibacterial activity of P. granatum leaf extract and identifies Epicatechin, Kaempferol, and Apigenin as potential lead compounds for developing novel therapies against MDR E. coli. These findings underscore the potential of plant-based compounds in combating antibiotic resistance and provide a foundation for further research into phytopharmaceuticals as alternative treatments for bacterial infections.
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