Jane C. is a Senior Reporter at NBC News. She specializes in storytelling that spans a variety of themes, with a focus on impactful narratives in health and science. Jane's work has been featured in notable publications such as BMC, MDPI, Albuquerque Journal, and Slate Magazine.
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Jane C. focuses on government and politics, with a strong emphasis on legal policy regulation and government announcements. Her coverage includes topics such as elections, law, voting, and medical research.
For effective outreach to Jane C., consider providing expert commentary or data-driven insights related to recent legal or regulatory changes within the political landscape. Additionally, pitches that align with her interest in specific states like Pennsylvania, Arizona, Alabama, Michigan, and Texas may be particularly relevant given her coverage of local developments.
Given the substantial portion of articles focused on law-related content (32%), offering perspectives from legal experts or those deeply involved in governmental processes could enhance engagement with Jane C.'s reporting interests.
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By: Veena S., Ti-Chun, Chang, Chisato, Li, Rana, Jane C., Nianwei, Zhonghan, Patil, Tariq M., Chao, Steven R., Lin, Burns, Shimizu, Kung-Yen
Thousands of large intergenic noncoding RNAs (lincRNAs) have been identified in the mammalian genome, many of which have important roles in regulat...
By: Jane C., Caitlin R., Chien-Wei, Srivastava, Whelan, Nair, Wang, Mcentee, March, Trisha, Anubhuti, Eliza K., Hanson, Rebecca J.
The CA125 epitope within the MUC16 tandem repeat region is detected via the CA125 II test for ovarian cancer surveillance. This test utilizes the M11 and OC125 antibodies. A revised model of MUC16 with 19 tandem repeats has recently been identified, including splice variants that exclude entire repeats. Additionally, OC125 has exhibited gaps in coverage of the tandem repeat region. To identify antibodies that bind more repeats and are suitable for spliceoform detection, more antibodies must be characterized using the revised model. This study characterized the binding of two M11-like and two OC125-like antibodies against the updated tandem repeat numbering system. 16 individual tandem repeats were expressed and purified. Binding interactions between each of the antibodies and recombinant repeats were examined by indirect enzyme-linked immunosorbent assay (ELISA) and surface plasmon resonance (SPR). The M11-like antibodies displayed different binding patterns when compared to each other, while the two OC125-like antibodies exhibited similar binding patterns. M11-like clone M77161 bound to all 16 repeats tested, indicating that it may be suitable for accurate detection of CA125. These findings demonstrate how different antibodies vary in their binding to CA125, contributing to ongoing development of improved clinical and research tools for ovarian cancer.
By: Harry Feinstone, Elgin Henry, Dharani Narayan
By: David, Moshkforoush, Gonzales, Klug, Jane C., Lee, Nikolaos M., Michael I., Hill, Eubanks, Tsoukias, Shui, Arash, Bo, Nelson, Mark T., Nicholas R., Kotlikoff, Albert L., Frank K.
The essential function of the circulatory system is to continuously and efficiently supply the O2 and nutrients necessary to meet the metabolic dem...
By: Downes, Evans, Atkins, Alaynick, Collins, Bright, Yu, Wall, Suh, Annette R., Christopher, Kefeng, Fan, Andrew Taylor, Michael, Jae M., Whyte, Ronald M., Jane C., Christopher E., Jamie, Robert K.,, Ruth T., William A.,, Brett, Weiwei, Li, Liddle, Naviaux
Mitochondria are highly adaptable organelles that can facilitate communication between tissues to meet the energetic demands of the organism. Howev...
