Jason Ence

With the Cougars boasting one of the best rosters in the nation, LJ Cryer and company should thrive against a Tigers squad already making headlines for all the wrong reasons.

Notre Dame needs every win it can get to play host in the College Football Playoff, and it'll make a statement against the Virginia Cavaliers.

Our betting preview for Jamaica vs. USA doesn't expect much scoring action, as Team USA would prefer to keep things clean and head back to America with at least one point.

The BYU Cougars have been living a charmed life this season, but Jason Ence's Week 12 upset picks believe their luck will run out vs. the Kansas Jayhawks on Saturday.

Our expert college football predictions expect the defenses to have the upper hand when the Tigers meet the Panthers.

The Kansas Jayhawks are enduring a season to forget with a 3-6 record, but Devin Neal has been a standout performer.

Team USA will have even more of a personnel advantage than they did in Jamaica when they beat the Reggae Boyz on their home turf on Thursday. Monday's matchup in St. Louis should be a win and a clean sheet for the Americans.

The UCF Knights keep losing close games, and their pass defense has been a major culprit. Garrett Greene and West Virginia can expose this unit in Morgantown on Saturday, per our college football upset picks.

Both Penn State and Minnesota feature outstanding defenses that rank among the best in the country, so even if the 45.5 total is relatively low, it's not low enough to avoid betting on the Under.

Our expert college football predictions expect points to come at a premium but Aggies wideout Amari Daniels should find the end zone at least once tonight.