José Gabriel

The Venezuelan actress Gaby Espino shared, with her 13.8 million followers on Instagram, the reason behind her prolonged absences on social networks.

With two issues under his arm and a heated controversy, this invention reaches the world Anna Indiana is a fact.

The film promotes the idea that any dream can be achieved with work and sacrifice. “Gol Gana” is now in theaters.

Álex Ubago was inspiration, nostalgia, poetry and voice, this Thursday, December 14, during his only presentation at the Chacao Cultural Center.

Brain–computer interfaces (BCIs) that integrate virtual reality with tactile feedback are increasingly relevant for neurorehabilitation in spinal cord injury (SCI). In our previous case study employing a BCI-based virtual reality neurorehabilitation protocol, a patient with complete T4 SCI experienced reduced pain and emergence of non-spastic lower limb movements after 10 sessions. However, it is still unclear whether these effects can be sustained, enhanced, and replicated, as well as the neural mechanisms that underlie them. The present report outlines the outcomes of extending the previous protocol with 24 more sessions (14 months, in total). Clinical, behavioral, and neurophysiological data were analyzed. The protocol maintained or reduced pain levels, increased self-reported quality of life, and was frequently associated with the appearance of non-spastic lower limb movements when the patient was engaged and not experiencing stressful events. Neural activity analysis revealed that changes in pain were encoded in the theta frequency band by the left frontal electrode F3. Examination of the lower limbs revealed alternating movements resembling a gait pattern. These results suggest that sustained use of this BCI protocol leads to enhanced quality of life, reduced and stable pain levels, and may result in the emergence of rhythmic patterns of lower limb muscle activity reminiscent of gait.

Insects are good examples of ground locomotion because they can adapt their gait pattern to propel them in any direction, over uneven terrain, in a stable manner. Nevertheless, replicating such locomotion skills to a legged robot is not a straightforward task. Different approaches have been proposed to synthesize the gait patterns for these robots; each approach exhibits different restrictions, advantages, and priorities. For the purpose of this document, we have classified gait pattern generators for multi-legged robots into three categories: precomputed, heuristic, and bio-inspired approaches. Precomputed approaches rely on a set of precalculated motion patterns obtained from geometric and/or kinematic models that are performed repeatedly whenever necessary and that cannot be modified on-the-fly to adapt to the terrain changes. On the other hand, heuristic and bio-inspired approaches offer on-line adaptability, but parameter-tuning and heading control can be difficult. In this document, we present the K3P algorithm, a real-time kinematic gait pattern generator conceived to command a legged robot. In contrast to other approaches, K3P enables the robot to adapt its gait to follow an arbitrary trajectory, at an arbitrary speed, over uneven terrain. No precomputed motions for the legs are required; instead, K3P modifies the motion of all mechanical joints to propel the body of the robot in the desired direction, maintaining a tripod stability at all times. In this paper, all the specific details of the aforementioned algorithm are presented, as well as different simulation results that validate its characteristics.

Department of Physical Medicine and Rehabilitation, Rio Hortega University Hospital, 47007 Valladolid, Spain

Department of Science Didactics, Faculty of Humanities and Education Sciences, University of Jaén, 23071 Jaén, Spain

Barcia Durán, Dayasagar, et al. map the expression of immune checkpoints in human atherosclerosis and examine the influence of lipid-lowering treatments and type 2 diabetes to understand how immune checkpoint inhibitors worsen cardiovascular risk in survivors of cancer.

Department of Science Didactics, Faculty of Humanities and Education Sciences, University of Jaén, 23071 Jaén, Spain Psychol. Int.