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“Mistakes like these led to a poorly executed election which left many Harris County residents frustrated," Nelson said.

Christ United Methodist Church of Jackson voted overwhelmingly to disaffiliate from the UMC Mississippi Conference.

Musk removed the Twitter gold badge, a verification badge for "official" accounts, from the New York Times X page

More details have emerged revealing that the barrage intercepted by the USS Carney was much "more sustained" than initially reported.

Oregon board has decided to extend the pause on the essentials skills test until at least 2029 because of -- you guessed it -- racism.

According to the records, Obama arrived at the scene via motorcade, and a witness interview actually took place at the Obama residence.

Abstract. Purpose: Whilst there are several prognostic classifiers, to date there are no validated predictive models that inform treatment selection for oropharyngeal squamous cell carcinoma (OPSCC). Our aim was to develop clinical and/or biomarker predictive models for patient outcome and treatment escalation for OPSCC. Experimental Design: We retrospectively collated clinical data, and samples from a consecutive cohort of OPSCC cases treated with curative intent at ten secondary care centres in UK and Poland between 1999-2012. We constructed tissue microarrays, which were stained and scored for 10 biomarkers. We then undertook multivariable regression of eight clinical parameters and 10 biomarkers on a development cohort of 600 patients. Models were validated on an independent, retrospectively-collected, 385-patient cohort. Results: 985 subjects (median follow-up 5.03 years, range 4.73-5.21 years) were included. The final biomarker classifier - comprising p16 and survivin immunohistochemistry, high-risk HPV DNA in-situ hybridisation, and tumour-infiltrating lymphocytes predicted benefit from combined surgery+adjuvant chemo/radiotherapy over primary chemoradiotherapy in the high-risk group (3yr OS 63.1% versus 41.1%, respectively, HR=0.32, 95% CI 0.16 -0.65, p=0.002), but not in the low-risk group HR=0.4, 95%CI 0.14-1.24, p=0.114). On further adjustment by propensity scores, the adjusted HR in the high-risk group was 0.34,95% CI = 0.17-0.67, p=0.002, and in the low-risk group HR was 0.5, CI 95% = 0.1-2.38, p=0.384. The Concordance index was 0.73. Conclusions: We have developed a prognostic classifier, which also appears to demonstrate moderate predictive ability. External validation in a prospective setting is now underway to confirm this and prepare for clinical adoption.

"We’re looking at the instructions ... on how to create a kind of non-professional chemical weapon with cyanide," Herzog said.

Sheffield teenager and F4 driver, Rowan Campbell-Pilling, has been announced as The Children’s Hospital Charity’s newest Children’s Champion.

Abstract Transcranial direct current stimulation (tDCS) has been used extensively but research on its efficacy within the sport and exercise science realm has been inconsistent.