Samantha Lee

Fillmore the dog is the internet’s newest hero after waking up his family in Tustin to alert them of a fire that was raging in their garage, likely saving three lives, as well as his own.

You’re three cars back from the Wyoming border, eastbound on I-70, watching the sun drop behind the Rockies in your rearview. It’s the Wednesday before Thanksgiving and traffic has that stop-and-go rhythm—everyone trying to make it home by dinner tomorrow, brake lights flaring red every quarter mile. You check your phone. Your mom texted asking what time you’ll hit Kansas. You’re about to answer when the Subaru in front of you stops demanding and you stop harder and the Ford F-150 behind you doesn’t stop at all.

For the last few years, Canada has been sitting on the world stage as one of the foremost players in the tech scene. Largely due to its supportive government initiatives and highly skilled workforce, it’s been fostering innovation in a way other countries – Latin American and Southeast Asian markets, for instance – have struggled to keep up with.

A curated monthly social calendar, featuring F1 X Louis Vuitton, Harmony Holiday and a Gucci exclusive.

For a small production of “This Is Our Youth,” two young actors took on the impossible task of self-producing a play in Los Angeles.

Colorado ranks among the states with rising safety concerns: With a +27.82% increase, Colorado saw motorcycle fatalities climb from 133 to 170, marking a significant year-over-year deterioration.

KEY HIGHLIGHTS Colorado ranks 7th in the nation for per capita political ad spending on Meta, with $69,706 spent per 100,000 residents. Colorado ranks 12th in total raw ad spending at $4,231,005, making it one of only two states with populations over 6 million to appear in the per capita top 10. Colorado’s per capita […]

Objectives To evaluate the efficacy and safety of low concentration atropine eye drops for reducing progression of myopia in children in the UK.Design Multicentre, double masked, superiority, placebo controlled, randomised trial.Setting National Health Service hospital eye services and academic institutions at five UK centres.Participants 289 children aged 6-12 years with myopia between −0.50 and −10.0 dioptres (D). Participants were allocated in ratio of 2:1 to atropine or placebo.Interventions One eye drop of preserved atropine 0.01% or placebo daily for two years.Main outcome measures The primary outcome was spherical equivalent refractive error of both eyes measured by autorefractor under cycloplegia after two years. Secondary outcomes included change in axial length, best corrected distance and near visual acuity, reading speed, pupil diameter, spectacle correction, adverse event rates, quality of life, and tolerability. Outcomes were collected every six months. An electronic monitoring system was used to assess adherence.Results 192 participants were included in the atropine group and 97 in the placebo group, with an average age of 9.3 years (standard deviation (SD) 1.7 years). 207 (72%) reported white ethnicity, 161 (56%) were girls, and the mean level of myopia was −2.87 D (SD 1.71 D). A total of 235 (81%) participants completed the study, with primary outcome data available for 230 (80%) participants: 151 (79%) in the atropine group and 79 (81%) in the placebo group. Atropine eye drops were more effective than placebo in reducing myopia progression (mean difference 0.33 D, 95% confidence interval (CI) 0.17 to 0.49 D, P<0.001). Prespecified subgroup analyses did not show differences according to age, ethnicity, sex, or severity of myopia. Changes in central axial length were significantly less in the atropine group versus placebo group: mean difference 0.14 mm (95% CI 0.07 to 0.21, P<0.001). There were no differences in other secondary outcomes, except pupil diameter, which was greater in the atropine group (0.36 mm, 95% CI 0.17, 0.55, P<0.001), and no differences in frequency of adverse events or in tolerability measures. No serious adverse events were related to the trial drugs.Conclusions Low concentration atropine (0.01%) eye drops significantly reduced progression of myopia and were well tolerated compared with placebo in children in the UK.Trial registration ISRCTN registry [ISRCTN99883695][1], ClinicalTrials.gov [NCT03690089][2].The code used to analyse the data in the paper can be found in the supplemental files. The data underlying the findings in this paper are openly and publicly available and can be found here: . If you encounter problems accessing the data, please contact the corresponding author.[1]: /external-ref?link_type=ISRCTN&access_num=ISRCTN99883695 [2]: /lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT03690089&atom=%2Fbmj%2F393%2Fbmj-2025-086698.atom

Japan and several countries near China are still broadly negative, with territorial disputes causing great concern.

Fiscal concerns and the interest rate gap between Japan and the United States weigh on currency.