Spencer Jones

For some patients with psoriasis, orally administered small molecule inhibitors of interleukin (IL)-17A may represent a convenient alternative to IL-17A-targeting monoclonal antibodies. This first-in-human study assessed the safety, tolerability, pharmacokinetics (PKs), and peripherally circulating IL-17A target engagement profile of single or multiple oral doses of the small molecule IL-17A inhibitor LY3509754 (NCT04586920). Healthy participants were randomly assigned to receive LY3509754 or placebo in sequential escalating single ascending dose (SAD; dose range 10–2,000 mg) or multiple ascending dose (MAD; dose range 100–1,000 mg daily for 14 days) cohorts. The study enrolled 91 participants (SAD,

FILE - New York Jets' Richard Caster (88), left, hauls in a second-period pass intended for Dallas Cowboys' Lance Rentzel (19) during an NFL football game Sept. 14, 1970, in

The New York Yankees have made a new offer to the Chicago White Sox for Dylan Cease, according to a report.

The Yankees and Blue Jays prospect teams square off on Saturday in one of the most anticipated matchups of MLB’s spring breakout series. Baseball America readers can live stream the game below, available via our partners at Send To News. You can find full Spring Breakout rosters for every team here.

Former Stanford men's basketball player Spencer Jones suggests that in the age of NIL, the university needs to do a better job of tangibly demonstrating the impact of its brand.

Welcome to the 12th (sheesh) edition of the 2024 weekly minor league roundup, where I review each Yankees affiliate from the week before and the prospects playing there. All in all, last week was a much better showing in Baby Bomber land than the week prior. There were both hitting and pitching performances worth getting excited about. Let’s dig in!

Pirates No. 19 prospect Jase Bowen cracks a two-run homer, his 4th of the year, at Double-A Altoona

Rays outfielder Jake Mangum tees off on a grand slam, his third homer of the year for Triple-A Durham

Welcome to the 21st edition of the 2024 weekly minor league roundup, where I review each Yankees affiliate from the week before and the prospects playing there. All but Triple-A is in its final week of regular season action, but there is still plenty of intrigue to be found on the farm. Let’s dig in!

Image credit: Bryce Eldridge (17) Sacramento River Cats vs Round Rock Express in a Triple-A PCL game at Dell Diamond in Round Rock, Texas on Sunday, September 15, 2024 (Photo by Eddie Kelly / ProLook Photos)