William Dean

Lagers and IPAs are being celebrated throughout May in Astoria, and everyone’s invited to the outdoor block parties.

The Jetty Juice Orange-Vanilla Hazy IPA, from North Jetty Brewing, was inspired by summer memories of orange creamsicles.

Mutant Skull, an ale made by Fort George Brewery as a tribute to Dead Man’s Isle, an Astoria tiki bar.

For Astorians, it’s more than a new taproom. It’s a salve for an emotional wound in the heart of the city.

Abstract: Objectives: To differentiate invasive lepidic predominant adenocarcinoma (iLPA) from adenocarcinoma in situ (AIS)/minimally invasive adenocarcinoma (MIA) of lung utilizing visual semantic and computer-aided detection (CAD)-based texture features on subjects initially diagnosed as AIS or MIA with CT-guided biopsy. Materials and Methods: From 2011 to 2017, all patients with CT-guided biopsy results of AIS or MIA who subsequently underwent resection were identified. CT scan before the biopsy was used to assess visual semantic and CAD texture features, totaling 23 semantic and 95 CAD-based quantitative texture variables. The least absolute shrinkage and selection operator (LASSO) method or forward selection was used to select the most predictive feature and combination of semantic and texture features for detection of invasive lung adenocarcinoma. Results: Among the 33 core needle-biopsied patients with AIS/MIA pathology, 24 (72.7%) had invasive LPA and 9 (27.3%) had AIS/MIA on resection. On CT, visual semantic features included 21 (63.6%) part-solid, 5 (15.2%) pure ground glass, and 7 (21.2%) solid nodules. LASSO selected seven variables for the model, but all were not statistically significant. “Volume” was found to be statistically significant when assessing the correlation between independent variables using the backward selection technique. The LASSO selected “tumor_Perc95”, “nodule surround”, “small cyst-like spaces”, and “volume” when assessing the correlation between independent variables. Conclusions: Lung biopsy results showing noninvasive LPA underestimate invasiveness. Although statistically non-significant, some semantic features showed potential for predicting invasiveness, with septal stretching absent in all noninvasive cases, and solid consistency present in a significant portion of invasive cases.

Goblins, gremlins and ghouls will soon be filling North Coast brewpubs and taprooms.

Goblins, gremlins and ghouls will soon be filling North Coast brewpubs and taprooms.

Goblins, gremlins and ghouls will soon be filling North Coast brewpubs and taprooms.

Highgate Primary School headmaster William Dean explains why art is a serious subject in school.

Seaside-based Sisu Brewing Co. is planning to expand into downtown Astoria with a brewpub and brewery.