David L

Abstract Guanine exchange factors (GEFs) are considered hard to drug with conventional small molecules, they lack conventional deep binding pockets and binding ligands are seldom reported.

Abstract Genome analyses reveal that gene duplication in eukaryotes is pervasive, providing a primary source for the emergence of new genes.

Three days ago, winter officially began, the longest night of the year. In the days following in the northern hemisphere, the darkness of the world begins to give way to light, as we anticipate the coming of the Savior.

“On the fourth day of Christmas, my true love gave to me, four calling birds ...” No, you didn't time travel back to the 2014 Christmas Price Index.

If you hang around this life long enough, you get old enough. As of today, I am seventy years of age -- a new decade, and another reminder of how far I've gone.

“On the sixth day of Christmas, my true love gave to me, six geese a-laying ...” The geese are on a growth streak and they're one of the most volatile gifts in this year's index.

It happens sooner or later, usually about this time of year, when the aforementioned year must end, and another one begins anew. And so we visit once again, the tradition of how others review the year in video form.

the daily musings ... of faith and culture, of life and love, of fun and games, of a song and dance man, who is keeping his day job.

“On the ninth day of Christmas, my true love gave to me, nine ladies dancing ...”

Abstract Projected atmospheric CO2 rise, coupled with intensification of drought in many regions, impacts the physiology of C3 plants beyond photosynthesis and carbon metabolism.