Jiao Tong

Abstract Multiple receptor analysis-based DNA molecular computation has been developed to mitigate the off-target effect caused by nonspecific expression of cell membrane receptors.

Abstract Physical exercise effectively prevents anxiety disorders caused by environmental stress. The neural circuitry mechanism, however, remains incomplete.

Abstract Brain anatomy plays a key role in complex behaviors and mental disorders that are sexually divergent.

Abstract The striatum, a core brain structure relevant for schizophrenia, exhibits heterogeneous volumetric changes in this illness.

MSX1 phase separation are associated with cleft palate. Here the authors show that MSX1 phase separation, triggered by its N-terminal intrinsically disordered region and regulated by PRMT1-catalyzed methylation, is a vertebrate-conserved mechanism for embryonic palatal development.

Industrial policies influence national economic development by allocating industrial land resources. Unlike the market-oriented industrial land transaction systems in developed countries, China's industrial land transactions are significantly influenced by governmental intervention. However, there is insufficient research on the extent and mechanisms of industrial policy's influence on land use costs in this context. Therefore, this study combines land transactions, industrial policy, urban statistics, and listed company data, creating a dataset of 9705 land transactions from 2011 to 2020 to analyze industrial policies' impact on land use costs. The findings are as follows: First, different industrial policies have differentiated effects on land use costs, with lower costs for key industries and higher costs for heavily polluting industries. Second, the impact is more pronounced when the land parcel is situated outside the development zone, transferred by the prefecture-level city government, and the proportion of the tertiary industry in the province is relatively low. Third, local governments achieve regulation of land use costs through industrial policies by employing listing method and transferring land to state-owned enterprises. Furthermore, subsequent investigations reveal that industrial policies can mitigate the decline in total factor productivity caused by increased land use costs for enterprises. This article holds significant implications for optimizing industrial land resource allocation and facilitating industrial transformation and upgrading in developing countries.

Abstract Understanding the heterogeneity of epigenetic modifications within single cells is pivotal for unraveling the nature of the complexity of gene expression and cellular function.

Abstract Precise and long-term electroanalysis at the single-cell level is crucial for the accurate diagnosis and monitoring of brain diseases.

Yinmin Wang ∙ Xiuxia Wang ∙ Zhaoqi Yuan ∙ Fei Liu ∙ Xusong Luo [email protected] ∙ Jun Yang

Abstract Background Osteoporosis and sarcopenia frequently occur in patients with end-stage renal disease undergoing hemodialysis (HD), and