Kiera Liblik

1. In this randomized controlled trial, fidanacogene elaparovovec therapy significantly reduced the mean annualized rate of bleeding in adult men with hemophilia B.

1. In this randomized controlled trial, in patients with both moderate-severe obstructive sleep apnea (OSA) and obesity, it was found that tirzepatide treatment reduced the occurrence of apneas and hypopneas.

1. In this randomized controlled trial, extended lymphadenectomy did not improve disease-free or overall survival in patients with muscle-invasive bladder cancer who were undergoing a radical cystectomy.

1. In patients with advanced leiomyosarcoma, a regimen of doxorubicin-trabectedin was superior to doxorubicin alone in improving progression-free and overall survival.

1. Ziresovir, an antiviral drug targeted at respiratory syncytial virus (RSV), was superior to placebo in reducing signs and symptoms of hospitalized young children with RSV infection.

1. Among patients with hereditary hemorrhagic telangiectasia (HHT), pomalidomide significantly reduced the severity of epistaxis and improved quality of life.

Originally published by 2 Minute Medicine view original article ). Reused on AccessMedicine with permission.

Originally published by 2 Minute Medicine view original article ). Reused on AccessMedicine with permission.

1. Zodasiran, an RNA interference (RNAi) therapy targeting angiopoietin-like 3 (ANGPTL3), resulted in a dose-dependent reduction in ANGPTL3 and triglyceride levels in patients with mixed hyperlipidemia.

1. In this randomized controlled trial, among adolescent girls and young women, it was found that twice-yearly lenacapavir resulted in a significantly reduced human immunodeficiency virus (HIV) incidence.