Lisa M. is a reporter at The San Jose Mercury News/Bay Area News Group publications. She specializes in covering science, medicine, and water-related topics, with a focus on the Wow beat, which encompasses a range of themes within applied sciences and healthcare. Lisa's work has been featured in numerous prominent outlets, including The Mercury News, East Bay Times, and Nature Portfolio, among others.
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Lisa M. primarily focuses on scientific research, healthcare, and pharmaceutical topics, with a strong emphasis on citing data in her articles. She tends to cover a wide range of medical research areas such as immunology, genetics, pediatrics, and cancer research.
Given the nature of Lisa's coverage attributes and themes covered, she would likely be responsive to pitches from experts or researchers who can provide valuable insights based on recent data or studies related to medical research topics. It is crucial for any outreach to demonstrate relevance by aligning with the specific focus of her articles and offering new perspectives backed by robust data analysis.
It is important to note that Lisa does not have a specified geographic focus but appears open to covering global scientific developments within the medical field.
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By: Julian C., Rayner, Anna, Lisa M., Waller, Flores, Victor, Lilley, Kuroshchenkova, Koreny, Chisholm, Scott A., Breckels, Konstantin, Ross F., Kathryn S., Alison, Nicolas, Barylyuk, Kemp
Chisholm et al. use hyperLOPIT spatial proteomics to map 1646 Plasmodium falciparum proteins across 24 subcellular compartments, revealing evolutionary patterns that have shaped malaria parasite biology and ongoing adaptive responses.
By: William H. Darr, Bradley Nelson, Zoological Pathology
By: Fike, Kathleen, Dyer, Frederick, Katherine, Truett, Landon, Lisa M., Donais
Radiology is a specialty that takes years of education and training to master. However, it is not uncommon for providers of all backgrounds to need to order imaging at some point in their career for a variety of diagnoses. It is helpful to have a basic knowledge of...
By: Pelet, Elnagdy, Piralla, Clotet, Timokratis, Sabrina, Gonzales, Anaya, Constantinescu, Carlos D., Diallo, Anastasiia, Shorte, Po-Ki, Pascal, Elena, Didier, Ana De, Murkesh, Florkin, Connolly, Couffignal, Tayfun, Morelle, Sørensen, Inés Marín, Andrew L., Hedestam, Thy, Bos, Dan A. I., Cruz, Dillies, Lantz, Ramirez, Liliana, Pieter R., Gagro, Monneret, Cognasse, Minh, Nussenzweig, Rambaud, Rebeca Perez, Husebye, Sandrine, Ekwall, Carola, Bozdemir, Tanaka, Tserel, Ku, Metz, Desguerre, Patrick, Kwok, Juan José Cáceres, Ricaurte, Aguiló-Cucurull, Heunks, Casasnovas, Bryceson, Vignali, Quentin, Ufuk, Hélène, Castelli, Seng, Gayretli, Duvlis, Rebeca, Veislinger, Picado, Mentré, Meunier, Fusco, Schidlowski, Amat, Wu, Bleibtreu, Albisures, Van Baarle, Esra Akyüz, Ozkaya-Parlakay, Nacho, Ecobichon, Enninga, Raphael, Bogunovic, María Soledad, Manchon, Palmero, Clément, Soumaré, Richard, Maillot, Lilleri, Rothenbuhler, Clercq, Tomohiro, Yves, Laviolle, Jacinta, Stilma, Beretta, Esmeralda Nuñez, Yeray Novoa, Estelle, Modi, Javier, Castelle, Kahina, Charles, Leo, Euvrard, Analia Gisela, Marie, Ferrer, Planas-Serra, Mohammed, Esperou, Kitty S. C., Cliona, Espérou, Nadine, Emine Hafize, Mirsaeidi, Yükselmiş, Minerva, Conlon, Rieux-Laucat, Schuurman, Cédric, Sabina, Véronique, José Alejandro Daza, Thomas, De Bree, Bettini, Gabriele, Emilie, Contro, Liam, Sigifredo, Ahmad Abou, Troya, Lemaignen, Eva, Jorg, Emma, Carrillo, Notarangelo, Kido, Ruiz, Dorival, Bourgeois, Karita, Josep Trenado, Särekannu, Gunst, Jonathan Antonio Roblero, Paulus, Kafif, Moncada-Vélez, Lam, Rigo-Bonnin, Fellay, Sara, Laurence, Casanova, Abir, Van De Beek, Carine, Maria Pilar Etxart, Lau, Bram, Martín Castillo, Imran, Mélodie, Rice, Darazam, Irene, Humbert, Bouvattier, Dominguez-Garrido, Ilad Alavi, Papadopoulos, Mateus V., Tardy, Moncomble, Marie-Alexandra, Ungeheuer, Osman, Tayoun, Diana M., Cuadros, Benkerrou, Cheng-Lung, Andrés, Justin, Jozefien De, Marie-Eve, Meersseman, Lucila A., Solé-Violán, Solanich, Loic, Lee, Verónica Posada, Marina, Tucci, Merlani, Rojas-Villaraga, Azot, Stella, Guedj, Gülhan, Gut, Lucet, Tsang, Butte, Eberl, Van Agtmael, Dusan, Marie-Pierre, Uzunhan, Franco, Vincent, Diego, Hafkamp, David, Lindsey B., Montagne, Sedkaoui, Pawel, Van Der Werf, Giulia Maria, Dauger, Dorgham, Villain, Pham, Samia, Pierre-Louis, Peter K., Şadiye Kübra Tüter, Thoral, Bravais, David Ross, Maria-Claire, Veelo, Seeleuthner, Pistone, Cécile, José M., Montse, Salma, Rausell, Luis Antonio, María Jesús, Silvia, Luis M., Giuseppe, Yildiz, Rosen, Ahmed A., Lucie, Slim, Nathan, Zahir, Ana, Lennart, Bonta, Raúl, Perez-Tur, Gil-Herrera, Delphine, Redin, Meziane, Emmanuelle, Jeanne, Null, Fouchard, Maria Yolanda Ruiz Del, Lyonnet, Navarro, Guy, Hagin, Prins, Yelena, Villar-García, Blanca Garcia, Lopez, Iolanda, Lluis, Geijtenbeek, Audrey Giraud, Townsend, Laribi, Evangelia, Dobbelaere, Lisa M., Tavernier, Souad Mehlal, Niels, Ouedrani, Cheng, Sánchez-Montalvá, Ozgur, Philippot, Abad, Boyarchuk, Bruneau, Schrauwen, Bellani, Camillo, Christodoulou, Cinthia, Barrou, Nemirowskaya, Alshahrani, Diouf, Amoura, Gérard, Francois, Joppe W., Bouiller, Antonio, Yu-Lung, Hariyan, Bonneaudeau, Stijnis, Letrou, Burrel, Manry, Simon J., Gribouval, Vandernoot, Nelli Y., Rozenberg, Vinh, Kurolap, Gérardin, Marcus J., Condino-Neto, Lefèvre, Ivan, Liina, Demar, Sene, Juan-Manuel, Yasar, Epaulard, Virginie, Okamoto, Caroline, Christophe, Paz-Artal, Alonso-Arias, Sonia, Sánchez-Ramón, Combes, Anya, Marleen A., Nikaia, Coşkuner, Michela, Bahram, Cyrus, Samira, Jeser Santiago Grass, Luis Felipe, Isabella, Mekontso-Dessap, Dorien, Lars, Paula Andrea Gaviria, Bosteels, Laura, Zatz, Lagier, Jia Li, Sébastien, Marie-Noëlle, Fernando, Jimeno, Le, Maslovskaja, Nadège, Horn, Hamann, Catharina, Castagnoli, Stéphane, Hagens, Horcajada, Jean-Luc, Stefan N., Tetyana, Delplancq, Perroquin, Noret, Hercberg, Endo, Richa, Dubos, Danion, Sigaloff, Agra, Toubert, Vught, Mansouri, Isabelle, Mojoli, Lescure, Leturque, Lampropoulou, Aschard, Keisuke, Neven, Mikko R.J., Marques, Kouakam, Henny, Magnone, Castro, Jacques G., Puéchal, Armand, Mouly, Garcia-Prat, Giulia, Anne-Sophie, Igor, Yuriy, Claire, Godelieve, Hemke, Taj Ali, Schweitzer, Erik, Mireille, Özçelik, Payet, García, Toubiana, Ozcelik, Mark S., Ikram, Juliette, González-Montelongo, Martijn, Bondarenko, Catherinot, Gulsum Iclal, Nollaig, Rosa-Calatrava, Petter, De La Chapelle, Schwartz, Tandjaoui-Lambiotte, Citerio, Hoctin, Jan M., Ng, Casari, Denise, Sarah, Mohammad, Lonneke A., Samya, Gatineau, Martin P., Iglesias, Demoule, Amin, Legrand, Alkan, Vito, Conti, W. Joost, Montagna, Hammarström, Mambert, Rodríguez, Picone, Laurent, Eto, Utsumi, Anissa, Loubna, Francesco, Picod, Khoa Manh, Stefano, Hatem, Sean P., Sözeri, Guerder, Harris, Barreiros, Bloomfield, Rogge, Juana, Dijkstra, Auguet, Baris-Feldman, Luisa, Ocejo-Vinyals, Kwan, Smit, Lim, Zhiyong, Sophie, Jean, Betül, Antolí, Noonan, Céline, Nevin, Elisabeth, Sallette, Sanchez, Audrey, Kali, Heder, Elena W. Y., Gissot, Tubiana, Pession, Janneke, Lehacaut, Mariama, Eugene Y. K., Luis I., Zhi, Ploin, Lye, Julia, Megan A., O’Farrelly, Melki, Larissa Rb, Marine, Bezrodnik, Nikoletta, Mohammed S., Cassaniti, Bart N., Ghirardello, Juan, Triantafyllia, Peigne, Reddy, Alexis, Eleftherios, Guillaume, Marwa H., Machado, El Bakkouri, Anna M., Dalgard, Kanık-Yüksek, Holanda-Peña, Sahanic, Nadji, Cristian Alejandro Ricaurte, Matthieu, Merete, M. Luisa, France, Vidaur, Matuozzo, Gaymard, Sami, Dave A., Medina, Senoglu, Peter, Taccone, Hagit Baris, Diane, Lampasona, Matt, Pierre, Fontes, Kaya, Gökhan, Tom, Ksouri, Visseaux, Okada, Hugo, Zhang, Ottavia M., Susan, López-Collazo, Migaud, Huong, Levi, Victoria, Esther J., Resnick, Clémence, Tual, Pierre-Emmanuel, Lorenzo-Salazar, Yepes, Garcia, Lisa F. P., Bachelet, Zimmer, Anissa M., Rossignol, Daniela, Rapti, Neves, Thiery, Aldave, Endry H. T., Charles M., Giacomo, Julien, Susen, Hovius, Stanislas, Girona-Alarcón, Mouquet, Levy, Aliberti, Lubetzki, Milner, Miquel Alfonso, De Diego, Alenka, Acosta-Ampudia, Jeulin, Wahiba, Arthur M. C., Mathieu P., Aiuti, Cathérine, François, Rivet, Azoulay, Zwinderman, Carolien, Flores, Talouarn, Snow, Alex Serra, Guaqueta, Petrov-Sanchez, Henrickson, Syrigos, Hermine, Andrés Augusto, Loreto, Taner, Bolze, Smith, Yat Wah M., Sabater-Riera, Ahmet Osman, Pan-Hammarström, Raoult, Teresa, Hraiech, Mehdi, Vivien, Adrien, Nellen, Planas, Neant, Louapre, Frezouls, Roger, Alessandro, Morio, Christelle, Vanderlinden, Angelo G., Cooper, Amani, Jeaninne, Pellecer, Antoine, Garyphallia, Mcelheron, Anglicheau, Stoclin, Tancevski, Valsecchi, Linda, De Chambrun, Achille, Mond, Fré, Evangelos, Magali, Robert, Biggs, Antonio Morales, Heppekcan, Dimitri, Marta, D’Enfert, Adrián, Quentric, Dobbs, Kisand, Migeotte, Annabelle, Bartoli, Chrabieh, Arkin, Konstantinos, Liis, Haljasmägi, Ventzislava, Cumano, Bruhns, Schuetz, Volleman, Chahine, Pellegrini, Cazzaniga, Yurii, Sediva, Karolina, Hatipoglu, Gregersen, Ramaswamy, Bolivar-Prados, Lucarelli, Hansen, Fanny, Agatha, Marie-Agnès, Tangy, Le Nagard, Denis, Frederique, Barnaby E., Foti, Liu, Clotilde, Froidure, Michael, Granado, Younes, Thorball, Lucy, Satoshi, Jaafoura, Le Bris, Paolo, Joseph, Fievet, Ondrej, Samatha, Öz, Benech, Francisco, Peterson, Jonathan, Smadja, Alla, Lachaize, Kristina, Mège, Stuart G., Solis, Sevgi, Fabienne, Yasemin Kendir, Sergio, Jie, Stemann, Jaïs, Debard, Yhojan, Pérez-Fernández, Etienne, Persia, Saleh, Laia, Beudel, Bourgeon, Fung, Corsico, Jalila, Uddin, Desille-Dugast, Alan K. L., Özge Metin, Prado, Licari, Naesens, Anna, Stuart E., Roufai, Boulanger, Bax, Jade, Janette S. Y., Oriane, Seminario, Hollmann, Patin, Al-Mulla, Batten, Desvallée, Dana, Els, Fekkar, Parizot, Judit, Danielson, Brigitte, Steven M., Piemonti, Piquard, Papadaki, Oriol, Alexandre, Bhavsar, Shen-Ying, Enouf, Vabres, Rachel, Harm Jan, Karen Alejandra Cifuentes, Rodriguez-Gallego, Tellier, Alina, Ignacio, Valérie, Karine, Nakagama, Aubart, Fahd, Wiedemann, Nadif, Jérôme, Debray, Koning, David Martínez, Briones, Lucas, Gian Luigi, Morten Bagge, Kai, Ruiz-Rodriguez, Maude, Melike, Rovina, Beluze, Dehbia, Teunissen, Markus, Fleur Le, Julie, Keles, Eystein S., Rutger, Coelho, Andreakos, Wauters, Yahşi, Mane, Eugenia, Sathishkumar, Vlaar, Schinkel, Jean-Laurent, Rui, Quaresima, Kwok-Cheung, Rubén D., Ricard, Koukaki, J. Gonzalo, Feldman, Seijo, Chirouze, Marzana, Estela, Theo, Marry, Saks, Gumucio, Roger Colobran, Bergin, De Vera, Matthijs C., Romero, Alsina, Gustavo Andrés Salguero, Botdhlo-Nevers, Alkhater, Ivan F. N., Gunilla Karlsson, Rodríguez-Gallego, Anne, Can, Pourshahnazari, Gentile, Aldric, Ostrowski, Luis, Yoko, Imberti, Jérémie, Esther, Jan, Ciceri, Geoffroy, Pape, Michailidis, De Rotte, Pujol, Tomasoni, Carlos E., Valentina, Huda, Oualha, Ghosn, Sarah E., Albert, Jamila, Chair, Pérez-Díaz, Joshua D., Smeele, Virginia, Nouroudine, Rafaela, Jean-Louis, Bonfanti, Şefika Elmas, Sevtap, Schluter, Blanca Amador, Violette, Zins, Pesci, Gómez, Król, Kerry, Paulsen, Vidigal, Mordacq, Aoife, Mehmet, Geerlings, Aina, Aliénor, Beth A., Pagani, Marioli, Eleni, Deplanque, Bitker, Kenny, Willemke, Manish J., Coralie, Mclaughlin, Serge, Morange, Oliver, Hind, Bukhari, James R., Correales, Pilar, Juan P., Akcan, Carrabba, Raffaele, Nawal, Oscar Andrés Briceño, Donald C., Carolina Soledad, Morel, Rodrigo, Coulongeat, Aline, Barrera, Carapito, Thumerelle, Vuotto, Cvetkovski, Muriel, Jaap, Elisa, Jost, Behillill, Axelle, Nafati, Su, Yu, Paris, Peytavin, Grenier, Kohsuke, Gaussem, Leung, Alain, Daganou, Margit Anita Hørup, Materna, Maniatis, Gilles, Raasveld, Trine H., Victor Daniel, Laouénan, Van Der Valk, Mathilde, Bajolle, Mikko, El Baghdadi, Carole, Yoann, Houhou, Young, Hugues, Appelman, Valencia-Ramos, Siouti, Velez-Santamaria, José Luis, Hulot, Alpha, Aurora, Benjamin, Preckel, Marchal, Slaby, Bousfiha, Dujardin, Camille, Le Mestre, Kennelly, Bousquet, Bustamante, Dufouil, Diehl, Belot, Ouifiya, Garot, Matthews, Botta, David S. Y., Pascale, Arnau, Maria Rita P., Heijmans, Briseño-Roa, Ballester, Pesole, Allende, Le Hingrat, Bertholon, Pascreau, Aydın, Faure, De Jong, Jale Bengi, Bomers, Schultz, Eric, Mircher, Koutsoukou, Gálvez-Romero, Piseth, Dalmau, Saker, Ni Cheallaigh, Anavaj, James, Mirault, Scolari, Parola, Vogt, Boudhabhay, Zbigniew J., Florentia, Mezidi, Spencer, Gault, Yazdanpanah, Djossou, Debette, Parra-Martínez, Milena, Rowen, Bogaard, Perreau, Rafael Leon, Nadia, Sisse Rye, Hervé, Bayhan, Emiroglu, Andrés A.,, Bourke, Zawadzki, Kuentz, Soizic, Nguyen, Deriano, Bulle, Ho, Clavé, Nadhira, Fleuren, Erikstrup, Pueyo, François-Xavier, Colobran, Adam H., Mohammed J., Lung, Touvier, Adeline, Morgane, Tangye, Jerome, Tolstrup, Gulsum, Aïcha, Gilardin, Yazdan, Géraldine, Angoulvant, Goffard, Poulakou, Yang, Belgin, Wouters, David S., Hans, Soraya, Sobh, Hung, Chouchane, Demirkol, Carrie L., Jørgensen, Mikkelsen, Duc, Yacine, Rose Anne, Sancho-Shimizu, De Montmollin, Mariella, Dupont, Meyts, A. H. (Koos, Ole Birger, Michele, López, Andrejak, John, Soler, Luyt, Morandeira, Mizoguchi, Magnus, Lorenzo, Pérez, Lemonnier, Adam, Zeynep, Mirjam, Grimbacher, Martin, Marie-Thérèse, Marlet, Kasapcopur, Stéphane Le, Dany, Shintaro, Tipu, Ali, Van Praet, Elbers, Yvon, De Lamballerie, Halwani, Junko, Lila, De Munter, Lingas, Adem, Qiang, Lanternier, Alexa, Basmaci, Joan, Charles-Edouard, Marianna, Pereira, Osoul, De Pontual, Ilaria, Rabih, Reijnders, Moïse, Taupin, Grobusch, Alejandro D., Edgar, Mathian, Goldberg, Xavier, Bernuth, Rivière, Manuel, Espinosa-Padilla, András N., Asano, Descamps, Ferreres, Jouanguy, Got, Aurélie, Fabrice, Celik, Hans-Heinrich, Adrian, Ramos, Martín-Nalda, Borghesi, Nielly, De Prost, Téoulé, Gigante, Maria, Marion, Leslie, Agustí, Quiros-Roldan, Nagashima, Mogensen, Bastard, Rodriguez, Takaki, Sottini, Saliha, Lina, Helen C., Jacques, Chen, László, D’Ortenzio, Martinez, Borie, Tsonas, Hanitsch, Anderson, Houas, Matilde Valeria, Dehban, Jordan, D’Angio, Davood, Goorhuis, Cecile, Françoise, Comarmond, Rocamora-Blanch, Benno, K. M. Furkan, Erdeniz, Cyril E., Poissy, Catherine, Mireia, Miguel Fernandez, Slabbynck, Delmonte, Malvy, Benoit, Veliz, Pere, Fatemeh Saheb, Boisson, Dominique, Frank, Stephanie, Tardivon, Arquero, Vanessa, Alphonsine, Olov, Daniele, Alberto, Bauters, Yalcin Burak, Carmen, Flaig, Caseris, Sylvie, Qiu-Chen, Bizien, Hamzeh-Cognasse, Larsen, Jorinde, Pauline, Brunner, Gilg, Poncelet, Florianne, Lambrecht, Pauline Caraux, Volokha, Maurits C. F. J., Hoffmann, Anne Geke, Lina Marcela Acevedo, Amandine, Sotirija, Cannet, Marjani, Sofie, Bouadma, Abián Montesdeoca, Yenan, Jean Christophe, Kashyap, Basso, Kashimada, Hagit, Cloherty, Tsumura, Vanel, Nossent, Olivier, Reyes, Annereau, Alessandra, Deniz, Comoli, Maya, Aguilera-Albesa, Iryna, Shahrooei, Laine, Paul, Raquel, David M., Selda, Arias, Sakuntabhai, Antonin, Spaan, Rosain, Abel, Buis, Matthew L., Tso, Magalie, Ozguler, Leif Gunnar, Imai, Fumadó, Shohei, Godínez, Juan Carlos, Algera, Eloy, Ceschi, Bodo, Jean-François, Peng, Eduardo, Desai, Ménager, Patrizia, Cristian, Kimmoun, Kerroumi, Giovanna, Oscar, Menno D., Ana Maria, Jordi, Chakravorty, Codina, Stepanovskyy, Amina, Elsa, Aysun, Graziano, Romain, Rebillat, Nollaig M., Faivre, Miyuki, Giorgio, Million, Dechanet, Behillil, Dyer, Flore, Karim, Seyed Alireza, Biondi, Valentine, Marc Pineton, Jens, Ursini, Puel, Gaudet, Turvey, Hoste, Sanne, Íñigo-Campos, Léa, Filomeen, Marcel, Marie E., Andres, Charlotte, Carlos, Bennedikt, Rodero, Dubost, Bénédicte, Gail V., Rebeca Pérez De, Baldanti, Storgaard, Tak-Chiu, Alyanakian, Resmini, Roux, Peters, Lomazzi, Mateus C., Krishna, Mélanie, Michel C., Duval, Sandra, Frédéric, Falck, Jarvis, Mégarbane, Tiberghien, Salagianni, Linglart, Cloé, Brodin, Lieuwe, Maródi, Aleksandar, Tharaux, Di Sabatino, Michel, Landinez, Astrid, Dromer, Marseglia, Karbuz, Pouletty, Angélique, Darragh, Yasutoshi, Fartoukh, Alexander P. J., Capra, Bouscambert-Duchamp, David C., Frédérique, Michèle, Prando, Pina-Fuentes, Akifumi, Mullaert, Bugiani, Mayana, Jean-Sébastien, Seppänen, Chalumeau, Agnes, Agurtzane, Laura Rachele, Hadjadj, Domínguez-Garrido, Kann, Cobat, Jamme, Marcela, Thibault, Blázquez, Owen T. Y., David T. P., Schneider, Jeffrey J., Fabio, Romein W. G., Yady Nataly, Roussel, Damien, Aude, Luigi D., Francesca, Alvarez, Christian, Rojas, Elana, Aurélien, Dorothée, Ernesto, Yuk-Yung, Vicky, Blanca, Kévin, Jimmy, Boucherit, Wiersinga, Dauby, Yee-Sin, Heath, Dunne, Ingersoll, Bernard, Boutolleau, Silvia Patricia Zuniga, Mònica, Renia, Adriana, Hendou, Mateus, Laura Mancera, Dinh, Nukui, Blanco, Schuurmans, Bonaventura, Venet, Baldolli, Iciar, Alba, Itan, Ivo, Cordel, Jesus Marquez, Holland, Ding, Voiriot, Juan C., Quintin, Luisa Paola Duarte, Joost, Marilou, Haerynck, Terrier, Van Vugt, Daniel, Schmidt, Lima, Barzaghi, Levin, Takanori, Roy, Stéphanie, Yuval, Stéphane J., Kenichi, Marchioni, Gervais, Arnaud, Nancy Carolina González, Maria Grazia, Alavoine, Gallian, Mata-Martínez, Mayaux, João Farela, Kara, Suzan A., Avramenko, Marketa, Soler-Palacín, Gemma, Melián, Mironska, Seiamak, Karamitros, Christine N., Maxime, Fallon, Arrestier, Suzan, Geraldine, Llovich, Jean-Philippe, Charbit, Brent, Anuj, Lazaro, Girbes, Mickaël, Jose, Fausto, Millereux, Tuinman, Matthew P., Oksana, Vasiliki, De Bruin, Thorn, De Vries, Béziat, De Brabander, Stepanovskiy, Enrico, Jesús, Borrero, Mayka, Tristan, Bueno, Ruggero, Cyril, Colm, Drolet, Hancerli, Le Voyer, Horst, Shaw, Vélez, Conor, Novelli, Khan, Alex, Noémie, Klocperk, Khalil, Marc, Pedersen, Meloni, Félix, Philippe, Sabine M., Hasan, Bhavi P., Qian, Richard P., Federica, Monsalve, Burdet, Jérémy, Stepanian, Maite, Yun, Tzourio, Van Mourik, Brouwer, Christine, Esposito-Farase, Desmarets, Jairo David Torres, Hermans, Yurdagul, Edson Jose Adrian Bolanos, Pärt, Martin-Loeches, Laire, Catherine M., Garçon, Goehringer, Özkan, Vasse, Timsit, Lemee, Jorge, Ricart, Di Santo, Ludovic, Siguret, Lévy, Van Den Rym, Cornelis S., Duffy, Alcover, Shrikant, Antonia, Layidé, Philippine, Viel, Lasa, Chloé, Idris, Van Der Poll, Kılıç, Ruch, Shcherbina, Cervantes-Gonzalez, Arranz, Kizil, Blandinières, Waucquier, Meritet, Michiel, Alexandra, Allavena, Gorochov, Bousso, Al-Muhsen, Hsieh, Nevers, Das, Le Gac, Mergeay-Fabre, Botelho, Carolina, Kim, Majid, Darley, Perlin, Bertrand, Yeny, Zuccaro, Molly A., Riccardo, Hubert, Suzanne, Amelia, Selma Erol, Nathalie, Le Goas, Aytekin, Xosé Luis, Bruno, Diederik, Isabella Worlewenut, Marie S., Thierry, Niall, Charpentier, Paz, Yesilbas, Bilguvar, Lifton, Couffin-Cadiergues, Jakob Hjorth, Karahan, Bilbao, Schwikowski, Marije, Mantilla, Cohen, Tiffany, Jean-Christophe, Ling, Dongelmans, Matos, Aurore, Kaguelidou, Erich D., Li, Aslinur, Rossi, Jean W., Van Braeckel, Accordino, Andrea, Vergara, Chauvineau, Nicolas
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR) doubles with every 5 y of age from childhood onward. Cir...
By: Marialaura, Claudia A. M. Gandini, Redolfi, Francesca, Costa, Manzon, Stefano F., Anita, Lisa M., Pichiecchio, Ramusino
Mild cognitive impairment (MCI) is a clinical condition at the very beginning of dementia continuum whose heterogeneity prevents a precise prediction of clinical evolution. In this work, in a cohort composed of MCI, healthy controls (HC), and Alzheimer’s disease (AD) patients, graph theory (GT) was combined with virtual brain modelling (TVB) to extract the information on network topology and dynamics embedded in magnetic resonance imaging data. With this approach, the analysis was extended to a multiparametric space and brought from the group to the subject-specific level. The comparison of network properties in HC, MCI, and AD revealed a profound reshaping of brain connectivity, which mainly affected the default mode, limbic, attention, and somatosensory networks. Interestingly, positivity to AD biomarkers (Aβ and τ) in MCI correlated with network topology, while a TVB parameter (i.e., recurrent excitation) correlated with reduced global cognition (MMSE score). The combination of GT and TVB parameters was superior to the individual techniques alone in providing a subject-specific phenotype of MCI sensitive to molecular biomarkers and correlated (R2 ~ 70%) with neuropsychological scores. This, in turn, could form the basis for a more precise stratification in prodromic dementia leading, in future, to a personalized prediction of evolution and therapeutic intervention.
By: Pierce-Lundgren, Max Planck, Hhmi Janelia, Wei-Chung Allen, Laia Serratosa, Mohammed Abdal Monium
By: Brian L., Machado, Palmer, Shahnaza, Allman, Daniel, Inoue, Megan, Bussey, Lisa M., Dexter, Timothy J., Doyle, Hashad, Hamidullah
There has been conflicting evidence on the role of parvalbumin expressing neurons (PVNs) in the prefrontal cortex in working memory. Here, the authors show that prefrontal PVN activity scales with task demands during working memory, that optimal activity is critical for performance under conditions of increased delay length and interference, and that gamma-frequency stimulation of PVNs improves working memory performance.
By: Susan, Surkan, Arlene, Olajide, Bryce E., Mela, Peacock, O’Connell, Jewell, Adelugba, Lisa M., Stoliker, Krista, Lagimodiere, Lindsay, Megan, Susan.Chalmers@Csc, Travis, Reddick, Shelley, Chalmers, Christie, Boone
Background Older individuals represent a growing demographic in correctional institutions worldwide, many of whom are living with complex health and social needs. One area of concern is that older people in custody are at increased risk of developing, or are currently living with, neurocognitive issues such as dementia. This pilot study examined the preliminary diagnostic performance of several cognitive screening tools for detecting suspected cases of dementia when compared with a formal diagnostic assessment among older people in custody at a multi-level forensic psychiatric treatment centre in Saskatchewan, Canada. Results Data collection included administering cognitive screening tools to older people in custody (n = 28) and a formal diagnostic assessment for dementia by a geriatrician (n = 18). Findings revealed that (a) cognitive screening tools varied in the identification of possible dementia, with point estimates ranging from 21% (Canadian Indigenous Cognitive Assessment; CICA) to 43% (Community Screening Instrument for Dementia; CSI ‘D’), whereas 33% of participants were screened positive for cognitive impairment (Mini-Mental State Exam; MMSE); (b) approximately 39% were diagnosed with dementia and 17% with mild cognitive impairment; and, (c) certain screening tools (CICA and MMSE) perform better in classifying cases of dementia. Conclusions Preliminary evidence suggests variability in the diagnostic performance of the assessed cognitive screening tools. The CICA and MMSE show promise in discriminating older males in custody in a forensic psychiatric setting with dementia from those without.
By: Taylor E., Michael T., Matia B., Marley, Susanne I., Kaitlyn L., Lisa M., Charles V., Marla K.
DEK is an estrogen-responsive chromatin-remodeling protein broadly expressed in the murine and human brain, with high expression in memory-relevant regions such as the hippocampus. Prior work from our group and others has linked DEK loss to cellular features associated with Alzheimer’s disease and Alzheimer’s disease-related dementias. Notably, our group has demonstrated that DEK expression declines with increasing dementia severity in women, but not in age-matched men, suggesting a sex-specific relationship between DEK loss and cognitive vulnerability. Together, these findings support a potential neuroprotective role for DEK; however, functional consequences of DEK loss in vivo were unknown. Here, we examined behavioral and molecular consequences of Dek loss using male and female constitutive knockout (cKO) mice assessed across cognitive, sensorimotor, and affective domains. Across assays, Dek cKO mice of both sexes exhibited intact locomotor activity, anxiety-related behavior, sensorimotor gating, and fear-associated memory. In contrast, female Dek cKO mice displayed selective impairments in cognitive flexibility despite preserved spatial learning and memory, a phenotype not observed in males and indicative of female-specific vulnerability following DEK loss. This sex difference, observed during Morris water maze reversal learning, suggests disruption of hippocampal–prefrontal circuitry. Guided by known sex differences in hippocampal DEK expression, transcriptomic profiling of hippocampal tissue revealed shared and sex-specific consequences of Dek deficiency, including alterations in cytoskeletal organization, neuronal signaling, chromatin regulatory mechanisms, and cellular stress pathways. Collectively, these findings demonstrate sex- and cognitive-domain-specific effects of DEK loss and support further investigation of DEK in executive function and hippocampal–prefrontal cortex–mediated cognition.
By: Mari E., Lisa M., Richard J., Joseph S.
Seagrasses perform various critical functions within social–ecological systems, though populations have declined drastically. Restoring seagrass is crucial, requiring holistic consideration of ecological and human dimensions. To date, biophysical factors predominantly guide restoration and marine spatial planning (MSP). Sociocultural data underpin optimal and just restoration design, but remain a “missing layer” in MSP. To address this gap, we combined participatory mapping and ground-truthed remote sensing to map seagrass distribution, human activities, and place values in Sanday, UK. Local knowledge guided in situ surveys, co-producing Sanday’s first scientific seagrass records. We “found” two meadows absent from current seagrass modelling, mostly within protected areas, and highlighted corresponding human activities (notably shellfisheries) and values (humanistic and scientific). We propose three restoration priority sites, given seagrass extent, habitat protection, and compatible activities and values. This study demonstrates potential for transdisciplinary mapping to improve restoration planning, addressing the missing sociocultural layer and key gaps within MSP processes.
