Lisa M. is a reporter at The San Jose Mercury News/Bay Area News Group publications. She specializes in covering science, medicine, and water-related topics, with a focus on the Wow beat, which encompasses a range of themes within applied sciences and healthcare. Lisa's work has been featured in numerous prominent outlets, including The Mercury News, East Bay Times, and Nature Portfolio, among others.
Preston is the artificial intelligence that powers the Intelligent Relations PR platform. Meet Preston
San Jose, United States (Local)
Not enough data
Lisa M. primarily focuses on scientific research, healthcare, and pharmaceutical topics, with a strong emphasis on citing data in her articles. She tends to cover a wide range of medical research areas such as immunology, genetics, pediatrics, and cancer research.
Given the nature of Lisa's coverage attributes and themes covered, she would likely be responsive to pitches from experts or researchers who can provide valuable insights based on recent data or studies related to medical research topics. It is crucial for any outreach to demonstrate relevance by aligning with the specific focus of her articles and offering new perspectives backed by robust data analysis.
It is important to note that Lisa does not have a specified geographic focus but appears open to covering global scientific developments within the medical field.
This information evolves through artificial intelligence and human feedback. Improve this profile .
By: Véronique, Donald R., Gerber, R. Benny, Dawson, Perraud, Pitts, Dabdub, Simone, Wingen, Horne, Meinardi, Blake, Finlayson, Kalinowski, Barbara J., Donald, Matthew L., Andrew S., Jeremy R., Lisa M., Martinez, Jaroslaw
Sulfuric acid (H2SO4), formed from oxidation of sulfur dioxide (SO2) emitted during fossil fuel combustion, is a major precursor of new airborne pa...
By: Laura M., Lisa M., Marguerite B., Cory J.
Introduction Dry eye disease (DED) symptoms can impair activities of daily living (ADLs) and work productivity (WP). This post hoc integrated analysis of the phase 2b COMET-1 (NCT04498182) and phase 3 COMET-2 (NCT05285644) and COMET-3 (NCT05360966) studies explored the effectiveness of acoltremon ophthalmic solution 0.003% (ACO [Tryptyr®]), a recently approved treatment for DED signs and symptoms, on visual-tasking ADLs and WP. Methods These randomized, double-masked, vehicle (VEH)-controlled studies had similar designs and identical eligibility criteria, enrolling adults aged ≥ 30 years with prespecified DED signs and symptoms. Patients were randomized 1:1 to receive ACO or VEH in both eyes twice daily for 84 (COMET-1) or 90 (COMET-2 and COMET-3) days. The degree that DED symptoms interfered with visual-tasking ADLs and WP was assessed on visual analog scales (VAS; 0–100 mm). ADL/WP and Symptom Assessment iN Dry Eye (SANDE) questionnaires and safety assessments were collected on days 1, 14, 28, and 84/90. Least-squares (LS) mean change from baseline (CFB) and responder analyses were analyzed using analysis of covariance and Cochran–Mantel–Haenszel test, respectively. Results Positive treatment effects in favor of ACO (n = 584) versus VEH (n = 595) were observed for LS mean difference in CFB from days 14 through 84/90 in the ability to use electronic devices (day 14, − 4.4 [P = 0.0016]; day 28, − 5.4 [P = 0.0002]; day 84/90, − 3.4 [P = 0.0378]), a visual-tasking composite score (day 14, − 3.7 [P = 0.0023]; day 28, − 4.2 [P = 0.0012]; day 84/90, − 3.1 [P = 0.0307]), and WP (day 14, − 4.4 [P = 0.0104]; day 28, − 5.4 [P = 0.0028]; day 84/90, − 4.4 [P = 0.0229]). Responder analyses favoring ACO supported the meaningfulness of observed CFB reductions. The only ocular treatment-emergent adverse event with > 1.5% incidence was instillation-site burning or stinging (ACO, 50.2% [97.6% mild]; VEH, 3.2% [100% mild]). Conclusions These exploratory data suggest that ACO is associated with rapid and sustained improvements in visual-tasking ADLs and WP. Trial Registration COMET-1, NCT04498182; COMET-2, NCT05285644; COMET-3, NCT05360966.
By: Stolz, Jean-Alphonse, Poloyac, Xiaomin, Lisa M., Jiaoying, Larkin, Suzenet, Suofu, Khattar, Baranov, Paula A., Matthew J., Giulietta, Yablonska, Timothy R., Richardson, Jockers, Jia, Yanqing, Carlisle, Robert M., Lezon, Wei, M. Beth, Jean-Pierre, Gable, Erika, Li, Mara, Jinho, Brianna E., Baranova, Yalikun, Daniela, Ralf, He, Oxana V., Kim, Nicolas K., Mihalik, Wang, Enderby, Wehbi, Samuel M., Jiatong, Cecon, Donna B., Jingjing, R. Mark, Minnigh, Eric S., Diane L., Franck, Timothy M., Heath, Vanessa L., Sergei V., Leronni, Ferrando, Vilardaga, Friedlander, Gérald, Guillaumet, Kretz, Amanda C., Sullivan, Frédéric G., Di Benedetto, Svitlana
G protein-coupled receptors (GPCRs) are classically characterized as cell-surface receptors transmitting extracellular signals into cells. Here we ...
By: Stephanie L., Moran, Keong, Eileen A., Julia C., Peter M., Jason G., Lisa M., Monique E., Marie K., John R.
In 2024, the US Centers for Disease Control and Prevention (CDC) and National Institute of Standards and Technology (NIST) initiated an interagency collaboration to bolster preparedness in the event of a pandemic scenario due to high pathogenicity avian influenza A(H5N1) clade 2.3.4.4b viruses that had been circulating in North America since 2021. Multiple spillover events into mammalian species, including an outbreak among dairy cattle and a surge in human cases, spurred the development of RNA reference materials to assist with new diagnostics development and validation. With input from CDC on sequences, NIST generated three synthetic RNA materials of A(H5N1) hemagglutinin, neuraminidase, and matrix proteins 1 and 2 gene segments. Here, we describe the development and characterization of these reference materials utilizing droplet digital reverse transcription polymerase chain reaction. Through this collaboration, we were able to rapidly provide quantified, homogeneous, stable, and epidemiologically relevant RNA reference materials to the public to aid new assay development and validation. Graphical abstract
By: Stanek, Clarke, Cathrine, Sidman, Li, Shihabuddin, Tamsett, Cheng, Richard L., Michael G., Schlossmacher, Lingyun, Marco A., Seng H., Sardi, Passini, S. Pablo, Grabowski, Gregory A.,, Thomas J., Lamya S.,, Jennifer, Kinnecom, Lisa M.
Emerging genetic and clinical evidence suggests a link between Gaucher disease and the synucleinopathies Parkinson disease and dementia with Lewy b...
By: Vito J., Julian, Lawney, Peluso, Plymate, Leigh, Photopoulos, Tchaicha, Ho, Bango, Paolo, Jeffery L., Stephen R., Massimo, Svitlana, Ribeiro, Umar, Benjamin, Colm, Chetta, Adams, Radha, Takuma, Loda, Xueliang, Silvano, Scott M., Dehm, Palombella, Brian, Syamala, Ying, Ellis, Yeung, Mcgovern, Debora C., D’Anello, Lisa M., Mahmood, Kutok, Jeremy, Kalekar, Caroline F.,, Tyekucheva, Clyde, Csibi, Morrissey, Uo, Larimer, Bastos, Cornelia, Cacciatore, Zadra, Stefano, Huang, Laura, Butler, Karen, Alfredo, Gao, Sudeepa, Stephane, Bosari, Giorgia
A hallmark of prostate cancer progression is dysregulation of lipid metabolism via overexpression of fatty acid synthase (FASN), a key enzyme in de...
Antimicrobial resistance poses a global threat to public health. Mobile microbiological laboratories can enable environmental monitoring of
By: Yijen Lin, Josep Carreras Leukaemia, Porto Alegre, Thomas Jefferson, Hofstätter Azambuja, Upmc Hillman
MALT1 protease is an intracellular signaling molecule that promotes tumor progression via cancer cell-intrinsic and cancer cell-extrinsic mechanisms.
By: Xunlai, James D.,, Fike, Feng, Yuan, Yongbo, Jia, Dong, Peter W.,, Zhenfei, Zice, Lisa M., Yaoping, Crockford, Qing, Schiffbauer, Tang, Xiao, Pratt, Peng, Wang, Cai, David A., Shuhai
Chemosymbiosis may have been a key driver of early animal evolution and diversification. Yet evidence for animal–microbe nutritional partnerships i...
By: Lisa M., Patrick, Cardello
Trauma is a pervasive experience with profound implications for individuals’ development, yet its impact on career trajectories remains underexplored. Trauma can disrupt vocational identity, decision-making, and career adaptability, particularly among students...
