Robert Herpen

Treatment with tofersen in patients with superoxide 1 dismutase 1 ALS was linked to preservation of motor function, maintenance of muscle strength and reduction of disease-specific biomarkers, data show. “Mutations in SOD1, the gene encoding superoxide 1 dismutase-1 (SOD1), are present in 1% to 2% of all amyotrophic lateral sclerosis patients,” Sean E. Smith, MD, MPHS,

Presence of a protein-binding biomarker in a small cohort of adults with depression may be an indicator that suicidal ideation increases because of elevated stress, according to research from JAMA Psychiatry

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The odds for stroke in older adults was significantly higher for those who experienced parental divorce by their 18th birthday compared to those who did not, and higher for those of an older age, data show.

In a large cohort of patients with autoimmune diseases, treatment with biologic disease-modifying antirheumatic drugs was associated with reduced incidence of Parkinson's disease, data show.

An interpretive machine learning model may be a feasible method for measuring agitation in dementia as well as in predicting certain environmental factors that are likely to contribute to the condition, according to a study.

Among post-9/11 United States military veterans, mild traumatic brain injury was associated with unfavorable long-term outcomes, such as severe PTSD, when occurring around a traumatic event, researchers wrote in JAMA Network Open

An analysis of adults with malignant glioma revealed that men were diagnosed at a younger age and women had worse preoperative status, but researchers found no other sex-related differences or clinical advantage.

Adults in the United Kingdom with an ADHD diagnosis appear to have shorter lifespans compared with the general population, likely due to unmet health

Tracking lipid variability may be a reliable method of predicting dementia and cognitive decline among community-dwelling older adults, according to new research from Neurology.