ScienceDaily

Compared with pre-surgical (neoadjuvant) chemotherapy alone, adding perioperative immunotherapy -- given before and after surgery -- significantly improved event-free survival (EFS) in patients with resectable early-stage non-small cell lung cancer(NSCLC), according to researchers.

An HIV vaccine candidate triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.

The brain modulates visual signals according to internal states, as a new study by neuroscientists reveals.

Plants have special corrective molecules at their disposal that can make retrospective modifications to copies of genes. However, it would appear that these 'Tipp-Ex proteins' do not have permission to work in all areas of the cell, only being used in chloroplasts and mitochondria. A study has now explained why this is the case. It suggests that the correction mechanism would otherwise modify copies that have nothing wrong with them, with fatal consequences for the cell.

Physicists revealed a microscopic phenomenon that could greatly improve the performance of soft devices, such as agile flexible robots or microscopic capsules for drug delivery.

Researchers have made a significant discovery, identifying genetic connections between inflammatory bowel disease (IBD) and Parkinson's disease (PD). Their study highlights the potential for joint therapeutic strategies to target these two challenging disorders. The team used advanced genomic analysis techniques to investigate the genetic overlap between IBD and PD. Their findings point to mutations in the LRRK2 gene as a common element linking both conditions and identify novel genes that are likely to be affected in people experiencing both IBD and PD.

New cells discovered in human omental adipose tissue inhibit fat cell formation, revealing why 'apple' body shapes may pose higher metabolic health risks.

Engineers have demonstrated a simple computational approach for improving the linearization of power amplifiers (PA), such as those used in mmWave systems and other telecommunication systems. The proposed technique involves training small neural networks to directly estimate the coefficients of a polynomial for digital pre-distortion (DPD) based on their frequency response during calibration sweeps.

Are acoustic features of music and spoken language shared across cultures? Researchers recorded themselves performing traditional music and speaking in their native language. In all 50+ languages, the rhythms of songs and instrumental melodies were slower than those of speech, while the pitches were higher and more stable.

B cells can control responses of myeloid cells through the release of particular cytokines (small proteins that control the growth and activity of cells in the immune system), challenging the prevailing view that T cells are the principle orchestrators of immune responses. In individuals with Multiple Sclerosis (MS), abnormally active respiration in B cells drives pro-inflammatory responses of myeloid cells and T cells, leading them to attack the protective sheath (myelin) that covers nerve fibers, and leading to nerve damage that causes symptoms of MS.