Mukesh Kumar

Delhi Capitals (DC) recorded their first points in the TATA Indian Premier League (IPL) 2024 with a 20-run win over Chennai Super Kings (CSK). The Dr YS Rajasekhara Reddy ACA-VDCA Cricket Stadium, Visakhapatnam, witnessed a good all-round performance by DC that helped overcome the in-form CSK.

Field experiments were conducted to investigate an appropriate saline water management strategy to enhance the yield and irrigation water use efficiency (IWUE) of drip-irrigated onion. The effects on soil water–salt dynamics, growth parameters, IWUE and yield were assessed under different lateral spacings and irrigation treatments. The different treatments comprised two lateral spacings (45 and 60 cm) and four irrigation treatments (canal water, C; conjunctive use of canal and saline water in a 1:1 ratio, C

AimThe study aims to evaluate the antibacterial properties of ethanolic extracts from Clitoria ternatea and Camellia sinensis against pathogens causing UTI, wound pathogens, and other clinical bacterial infections and their cytotoxic effects using the brine shrimp lethality assay (BSLA).MethodsEthanolic extracts of C. ternatea and C. sinensis were prepared, and their antibacterial activity was tested against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Enterococcus faecalis using the well diffusion method. The cytotoxicity was assessed through the BSLA, determining the LC50 values for each extract.ResultsThe formulation of both plant extracts exhibited significant antibacterial activity against UTI pathogens, and wound pathogen bacteria showed higher efficacy compared to other studies. The BSLA revealed a dose-dependent increase in toxicity, with C. ternatea extracts demonstrating higher cytotoxicity than C. sinensis.ConclusionThe ethanolic extracts of C. ternatea and C. sinensis possess antibacterial properties against UTI-causing bacteria and show cytotoxic effects in a brine shrimp model. These findings suggest the potential of these plants for developing alternative treatments for UTI. However, further research is necessary to fully understand their safety and efficacy in human subjects.

India's naval developments in Lakshdweep and Agalega may trigger insecurities in the Indian Ocean region, turning it into a Zone of Stress

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Deep brain stimulation (DBS) has evolved substantially over the past decades. The technology first appeared in mainstream practice in the 1980s to treat Parkinson's disease (PD).

ObjectiveThis study aimed to synthesize cobalt nanoparticles (CoNPs) via the green synthesis method using Millettia pinnata (M. pinnata), leaf (MPL), Butea monosperma (B. monosperma) flower (BMF), and Madhuca indica (M. indica) flower (MIF) as eco-friendly reducing agents. It further aimed to compare the effectiveness of these plant extracts in CoNPs production and evaluate the antioxidant activities of the synthesized nanoparticles (NPs), establishing a link between the phytochemical constituents of the extracts and the antioxidant capacity of CoNPs for potential applications in drug development and environmental sustainability.Materials and methodsCoNPs were synthesized using aqueous extracts of MPL, BMF, and MIF. These extracts act as stabilizing and self-reducing agents. Initially, the presence of CoNPs was detected visually by observing a color change. To confirm this observation, UV-visible spectroscopy and Fourier transform infrared (FTIR) spectroscopy were employed. UV-visible spectroscopy helps in analyzing the absorption of light by the CoNPs, while FTIR spectroscopy is used to identify the functional groups present in the NPs. Subsequently, the antioxidant activity of the synthesized CoNPs was assessed using the 1,1-diphenyl-2-picryl hydroxyl (DPPH) radical-scavenging assay. This assay measures the ability of antioxidants to neutralize free radicals by determining the reduction in the DPPH radical's absorption. To ensure the reliability of the results, the experiments were conducted in triplicate. Statistical analysis was then performed to compare the antioxidant effectiveness of the different plant extracts used in synthesizing the CoNPs. This analysis helps in determining any significant differences in antioxidant activity among the extracts.ResultsUV-visible spectral analysis confirmed the successful synthesis of CoNPs, revealing characteristic absorption peaks. For M. pinnata leaf extract (MPLE), the maximum peak was observed at ~272 nm, while B. monosperma flower extract (BMFE) exhibited a peak at ~276 nm, and M. indica flower extract (MIFE) revealed a maximum peak at ~320 nm. FTIR analysis further validated the presence of organic molecules from plant components on the outer layer of CoNPs, indicating successful capping and stabilization by phytochemicals from the extracts. The spectra displayed various peaks at different wavenumbers: MPLE showed prominent peaks at 3335 cm−1, BMFE showed distinct peaks at 3314 cm−1, and MIFE exhibited significant peaks at 3261 cm−1. Among the three types of CoNPs tested, those synthesized using MIFE exhibited the highest inhibition of 87.67% at a concentration of 60 µL. This higher inhibition was compared to those synthesized using BMFE and MPLE. This study suggests that the CoNPs synthesized on MIFE can serve as an antioxidant agent because of their remarkable free radical-scavenging activity.ConclusionsThe study highlights the potential of CoNPs synthesized using MIFE as they exhibited superior antioxidant activity compared to those synthesized with BMFE and MPLE. Therefore, the study underscores the promise of MIFE as a valuable natural resource for producing CoNPs abundant in antioxidants. Furthermore, it emphasizes the importance of implementing environmentally friendly synthesis techniques to produce nanomaterials that are both safe for the environment and biologically effective.

New Delhi: Delhi Capitals beat Mumbai Indians by 10 runs in another high-scoring Indian Premier League match here Saturday.

The deadline to submit the preliminary squad for the T20 World Cup 2024 was kept as May 1. The Indian Board has named a 15-member squad for the global tournament. Notably from Rinku Singh to KL Rahul, there have been several players who have missed out from the team.

PATNA, May 1 -- Patna police on Tuesday arrested a man with 82 grams of drugs worth about Rs 50 lakh, besides Rs 86,000 in cash and a cell phone....