Maria Cristina

Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

GalaScreen Laboratories, Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy

VO2 is a promising phase change material offering a large contrast of electric, thermal, and optical properties when transitioning from semiconductor to metallic phase. Here we show that a hybrid metamaterial obtained by proper combination of a VO2 layer and a nanodisk gold array provides a tunable plasmonic gap resonance in the infrared range. Specifically, we have designed and fabricated a metal–insulator-metal gap resonance by inserting sub-wavelength VO2 film between a flat gold layer and a gold nanodisk resonator array. The resonance of the hybrid metamaterial is centered in the useful 3–5 μm range when VO2 is in its semiconductor state. The experimental study highlights a monotonical spectral tuning of the resonance when increasing temperature up to 50 °C above the room temperature, providing a continuous resonance shift of almost 1 μm in the mid-infrared range. Wavelength range and intensity tunability can be further optimized by modifying the thicknesses of the layers and metamaterial parameters.

Aconitine is a highly poisonous C19-diterpenoid alkaloid identified and isolated from the species of the genus Aconitum. Aconitine is indicated in the treatment of cardiovascular diseases (CVDs) and, due to its neurotoxic effects, is a very effective drug in pain release. A total of 101 relevant scientific papers were manually searched on the Web of Science, Scopus, Science Direct, Google Scholar, PubMed and Dovepress databases and in the books available in the library of the Department of Natural Sciences, the National University of Science and Technology POLITEHNICA Bucharest, Pitesti University Centre, Romania. In combination treatments, aconitine shows antiarrhythmic and anti-inflammatory activity, a synergistic antiproliferative effect and decreased reactive oxygen species (ROS) generation, an improved biodistribution and bioavailability. Additionally, the entrapment of aconitine in engineered nanoparticles represents a promising method for reducing the toxicity of this alkaloid. This review provides, for the first time, a comprehensive picture of the knowledge and research on the synergistic, additive and antagonistic effects of aconitine in combination treatments applied in vivo or in vitro. The summarized studies represent important clues in addressing the multitude of knowledge, which can find their utility in practical and clinical applications.

Typesetting math: 100% a t h a x /extensions/tex2jax.js Mindfulness-based interventions (MBIs) have shown effectiveness in promoting parents' and children's well-being.

This review paper explores the multifaceted relationship between sweet cherry nutrients and human health, aiming to uncover the comprehensive impact of these bioactive compounds from orchard to wellness. Furthermore, it highlights how advanced crop techniques can be pivotal in optimizing these beneficial compounds. Synthesizing existing literature, the paper examines the diverse bioactive nutrients in sweet cherries, including antioxidants, polyphenols, vitamins, and minerals, and elucidating their mechanisms of action and potential health benefits. From antioxidant properties to anti-inflammatory effects, the paper elucidates how these nutrients may mitigate chronic diseases such as cardiovascular disorders, diabetes, and neurodegenerative conditions. Additionally, it explores their role in promoting gastrointestinal health, enhancing exercise recovery, and modulating sleep patterns. The review discusses emerging research on the potential anti-cancer properties of sweet cherry compounds, highlighting their promising role in cancer prevention and treatment. Furthermore, it delves into the impact of sweet cherry consumption on metabolic health, weight management, and skin health. By providing a comprehensive overview of the current understanding of sweet cherry nutrients and their health effects, this paper offers valuable insights for researchers, healthcare professionals, and consumers interested in utilizing nature's bounty for holistic wellness.

This study compares various F1-score variants—micro, macro, and weighted—to assess their performance in evaluating text-based emotion classification. Lexicon distillation is employed using the multilabel emotion-annotated datasets XED and GoEmotions. The aim of this paper is to understand when each F1-score variant is better suited for evaluating text-based multilabel emotion classification. Unigram lexicons were derived from the annotated GoEmotions and XED datasets through a binary classification approach. The distilled lexicons were then applied to the GoEmotions and XED annotated datasets to calculate their emotional content, and the results were compared. The findings highlight the behavior of each F1-score variant under different class distributions, emphasizing the importance of appropriate metric selection for reliable model performance evaluation in imbalanced multilabel datasets. Additionally, this study also investigates the effect of the aggregation of negative emotions into broader categories on said F1 metrics. The contribution of this study is to provide insights into how different F1-score variants could improve the reliability of multilabel emotion classifier evaluation, particularly in the context of class imbalance present in the case of phishing emails.

Department of Veterinary Sciences, University of Turin, Largo Paolo Braccini 2, 10095 Grugliasco, Italy

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Abstract Healthy diets are known for their co-benefits of reducing environmental impacts and enabling the same agricultural resources to feed a larger human population.